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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGI1 All Species: 19.7
Human Site: S236 Identified Species: 48.15
UniProt: O95970 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95970 NP_005088.1 557 63818 S236 S Q D L P Y Q S L S I D T F S
Chimpanzee Pan troglodytes Q1EGL2 557 63773 S236 S Q D L P Y Q S L S I D T F S
Rhesus Macaque Macaca mulatta XP_001106283 675 75127 A358 Y Q T L S F P A V S A E P F L
Dog Lupus familis XP_534971 557 63799 S236 S Q D L P Y Q S L S I D T F S
Cat Felis silvestris
Mouse Mus musculus Q9JIA1 557 63625 S236 S Q D L P Y Q S L S I D T F S
Rat Rattus norvegicus Q8K4Y5 557 63709 S236 S Q D L P Y Q S L S I D T F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513725 484 55978 D180 D T F N T K N D V Y V A I A Q
Chicken Gallus gallus NP_001038120 526 60552 D222 D T F S Y M N D E H V V I A Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122241 543 62031 S235 S I S V E A F S Y G N D Q Y V
Tiger Blowfish Takifugu rubipres NP_001072089 536 60739 D232 I D T F D Y K D D V Y V T I G
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 44.1 99.2 N.A. 96.9 96.9 N.A. 52.2 82.5 N.A. 67.3 53.6 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 60.5 99.6 N.A. 98.3 98.1 N.A. 66.6 87.2 N.A. 82 69.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 100 N.A. 100 100 N.A. 0 0 N.A. 20 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 53.3 100 N.A. 100 100 N.A. 13.3 6.6 N.A. 33.3 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 0 10 10 0 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 10 50 0 10 0 0 30 10 0 0 60 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 10 0 0 10 0 0 0 % E
% Phe: 0 0 20 10 0 10 10 0 0 0 0 0 0 60 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 0 50 0 20 10 0 % I
% Lys: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 60 0 0 0 0 50 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 20 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 50 0 10 0 0 0 0 0 10 0 0 % P
% Gln: 0 60 0 0 0 0 50 0 0 0 0 0 10 0 20 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 0 10 10 10 0 0 60 0 60 0 0 0 0 50 % S
% Thr: 0 20 20 0 10 0 0 0 0 0 0 0 60 0 0 % T
% Val: 0 0 0 10 0 0 0 0 20 10 20 20 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 10 60 0 0 10 10 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _