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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGI1
All Species:
21.52
Human Site:
S473
Identified Species:
52.59
UniProt:
O95970
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95970
NP_005088.1
557
63818
S473
Q
D
I
Q
R
M
P
S
R
G
S
M
V
F
Q
Chimpanzee
Pan troglodytes
Q1EGL2
557
63773
S473
Q
D
I
Q
R
M
P
S
R
G
S
M
V
F
Q
Rhesus Macaque
Macaca mulatta
XP_001106283
675
75127
S591
S
E
V
Q
A
L
P
S
R
G
S
L
A
L
Q
Dog
Lupus familis
XP_534971
557
63799
S473
Q
D
I
Q
R
M
P
S
R
G
S
M
V
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIA1
557
63625
S473
Q
D
I
Q
R
M
P
S
R
G
S
M
V
F
Q
Rat
Rattus norvegicus
Q8K4Y5
557
63709
S473
Q
D
I
Q
R
M
P
S
R
G
S
M
V
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513725
484
55978
P408
R
G
A
M
I
L
Q
P
F
S
F
K
N
H
H
Chicken
Gallus gallus
NP_001038120
526
60552
P450
R
G
S
M
V
F
Q
P
L
Q
I
R
N
Y
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122241
543
62031
F465
P
S
R
G
S
M
V
F
Q
P
V
S
I
G
N
Tiger Blowfish
Takifugu rubipres
NP_001072089
536
60739
P460
R
G
S
M
V
L
Q
P
F
S
F
K
E
R
H
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
44.1
99.2
N.A.
96.9
96.9
N.A.
52.2
82.5
N.A.
67.3
53.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
60.5
99.6
N.A.
98.3
98.1
N.A.
66.6
87.2
N.A.
82
69.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
46.6
100
N.A.
100
100
N.A.
0
6.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
13.3
20
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
20
0
20
0
0
50
0
% F
% Gly:
0
30
0
10
0
0
0
0
0
60
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% H
% Ile:
0
0
50
0
10
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% K
% Leu:
0
0
0
0
0
30
0
0
10
0
0
10
0
10
0
% L
% Met:
0
0
0
30
0
60
0
0
0
0
0
50
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
10
% N
% Pro:
10
0
0
0
0
0
60
30
0
10
0
0
0
0
0
% P
% Gln:
50
0
0
60
0
0
30
0
10
10
0
0
0
0
70
% Q
% Arg:
30
0
10
0
50
0
0
0
60
0
0
10
0
10
0
% R
% Ser:
10
10
20
0
10
0
0
60
0
20
60
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
20
0
10
0
0
0
10
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _