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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP15
All Species:
15.45
Human Site:
S178
Identified Species:
34
UniProt:
O95972
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95972
NP_005439.2
392
45055
S178
S
S
K
P
S
L
M
S
N
A
W
K
E
M
D
Chimpanzee
Pan troglodytes
XP_529247
393
45083
S178
S
S
K
P
S
L
M
S
N
A
W
K
E
M
D
Rhesus Macaque
Macaca mulatta
XP_001083980
393
45455
S178
L
P
K
S
S
L
M
S
N
A
W
K
E
M
D
Dog
Lupus familis
XP_549005
393
44984
S177
S
S
N
P
S
L
M
S
K
A
W
T
E
M
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0L4
392
44879
S176
S
S
K
P
S
P
M
S
K
A
W
T
E
I
D
Rat
Rattus norvegicus
Q6HA10
452
50994
P250
A
R
D
S
G
A
R
P
R
G
P
Q
Q
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510645
359
41050
P165
A
S
S
Q
L
Y
R
P
T
A
W
Q
E
T
D
Chicken
Gallus gallus
Q90752
405
46039
I196
L
S
E
R
S
Q
A
I
T
R
L
L
D
T
R
Frog
Xenopus laevis
P30885
401
45970
N193
T
A
N
G
H
M
I
N
R
L
L
D
T
R
V
Zebra Danio
Brachydanio rerio
A8E7N9
412
47049
K190
L
D
L
E
D
A
H
K
P
K
W
E
V
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
I174
S
R
T
R
L
N
S
I
V
S
L
K
D
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
93.8
74
N.A.
63.5
23.8
N.A.
41.5
26.1
25.6
25
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
98.4
95.6
84.2
N.A.
75.7
38.9
N.A.
56.6
42.9
42.8
44.1
N.A.
N.A.
N.A.
N.A.
43.8
P-Site Identity:
100
100
80
80
N.A.
73.3
0
N.A.
33.3
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
80
80
N.A.
80
20
N.A.
46.6
26.6
33.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
19
10
0
0
55
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
0
0
0
0
0
10
19
0
64
% D
% Glu:
0
0
10
10
0
0
0
0
0
0
0
10
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
19
0
0
0
0
0
10
0
% I
% Lys:
0
0
37
0
0
0
0
10
19
10
0
37
0
10
0
% K
% Leu:
28
0
10
0
19
37
0
0
0
10
28
10
0
0
0
% L
% Met:
0
0
0
0
0
10
46
0
0
0
0
0
0
37
0
% M
% Asn:
0
0
19
0
0
10
0
10
28
0
0
0
0
0
0
% N
% Pro:
0
10
0
37
0
10
0
19
10
0
10
0
0
0
10
% P
% Gln:
0
0
0
10
0
10
0
0
0
0
0
19
10
0
0
% Q
% Arg:
0
19
0
19
0
0
19
0
19
10
0
0
0
10
19
% R
% Ser:
46
55
10
19
55
0
10
46
0
10
0
0
0
10
0
% S
% Thr:
10
0
10
0
0
0
0
0
19
0
0
19
10
19
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _