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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
S1PR4
All Species:
8.18
Human Site:
S73
Identified Species:
20
UniProt:
O95977
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95977
NP_003766.1
384
41623
S73
L
V
L
A
A
I
T
S
H
M
R
S
R
R
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100113
384
41683
S73
L
V
L
A
A
I
T
S
H
M
R
S
R
R
W
Dog
Lupus familis
XP_854902
383
41632
T74
L
V
L
V
A
I
A
T
R
M
R
S
R
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0L1
386
42244
I76
M
V
L
A
A
I
A
I
Y
M
R
S
R
R
W
Rat
Rattus norvegicus
P48303
383
42727
K73
F
V
L
L
T
I
W
K
T
K
K
F
H
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520197
378
41947
K68
F
V
L
L
T
I
W
K
T
K
K
F
H
R
P
Chicken
Gallus gallus
XP_428050
381
42447
R69
L
V
L
L
A
V
L
R
C
L
R
A
R
R
W
Frog
Xenopus laevis
Q9PU17
366
41345
V78
L
V
M
V
A
I
Y
V
N
R
R
F
H
F
P
Zebra Danio
Brachydanio rerio
Q9DDK4
362
40583
A67
Y
Y
F
I
G
N
L
A
L
S
D
L
L
A
G
Tiger Blowfish
Takifugu rubipres
Q9PUQ8
384
42694
F67
R
F
H
N
R
M
Y
F
F
I
G
N
L
A
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
85.9
N.A.
82.1
39.5
N.A.
38
54.1
30.9
37.5
37.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.4
91.1
N.A.
89.6
58.8
N.A.
57.2
71
47.6
54.1
53.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
73.3
N.A.
73.3
26.6
N.A.
26.6
53.3
33.3
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
86.6
33.3
N.A.
33.3
73.3
46.6
6.6
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
60
0
20
10
0
0
0
10
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
20
10
10
0
0
0
0
10
10
0
0
30
0
10
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
20
0
0
0
30
0
0
% H
% Ile:
0
0
0
10
0
70
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
20
0
20
20
0
0
0
0
% K
% Leu:
50
0
70
30
0
0
20
0
10
10
0
10
20
0
10
% L
% Met:
10
0
10
0
0
10
0
0
0
40
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
0
10
10
10
60
0
50
70
0
% R
% Ser:
0
0
0
0
0
0
0
20
0
10
0
40
0
0
0
% S
% Thr:
0
0
0
0
20
0
20
10
20
0
0
0
0
0
0
% T
% Val:
0
80
0
20
0
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
50
% W
% Tyr:
10
10
0
0
0
0
20
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _