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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECK
All Species:
22.73
Human Site:
S149
Identified Species:
55.56
UniProt:
O95980
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95980
NP_066934.1
971
106457
S149
I
S
R
N
E
M
G
S
V
C
C
S
Y
A
G
Chimpanzee
Pan troglodytes
XP_520575
971
106469
S149
I
S
R
N
E
M
G
S
V
C
C
S
Y
A
G
Rhesus Macaque
Macaca mulatta
XP_001083599
971
106512
S149
I
S
R
N
E
M
G
S
V
C
C
S
Y
A
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0J1
971
106117
S149
I
S
R
N
E
M
G
S
V
C
C
S
Y
A
G
Rat
Rattus norvegicus
NP_001101424
920
100041
S149
I
S
R
N
E
M
G
S
V
C
C
S
Y
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521006
935
102603
G129
S
V
C
C
S
Y
A
G
R
H
T
N
C
R
E
Chicken
Gallus gallus
XP_418897
963
105683
S143
I
N
R
N
E
M
G
S
I
C
C
S
Y
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648733
1071
117775
R238
S
E
C
L
E
A
C
R
A
V
F
E
P
A
N
Honey Bee
Apis mellifera
XP_392031
925
102011
R138
T
C
A
L
S
G
S
R
R
N
L
N
E
S
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790172
719
79733
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.9
N.A.
N.A.
92.8
86.9
N.A.
85.7
83.8
N.A.
N.A.
N.A.
30.6
33.5
N.A.
34
Protein Similarity:
100
99.9
99.2
N.A.
N.A.
95.7
90.3
N.A.
91.2
90.8
N.A.
N.A.
N.A.
48.8
51.5
N.A.
47.9
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
86.6
N.A.
N.A.
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
100
N.A.
N.A.
N.A.
13.3
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
10
0
10
0
0
0
0
70
0
% A
% Cys:
0
10
20
10
0
0
10
0
0
60
60
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
70
0
0
0
0
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
60
10
0
0
0
0
0
0
60
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
60
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
20
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
60
0
0
0
0
0
10
0
20
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
60
0
0
0
0
20
20
0
0
0
0
10
0
% R
% Ser:
20
50
0
0
20
0
10
60
0
0
0
60
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
50
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
60
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _