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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RECK All Species: 23.03
Human Site: Y309 Identified Species: 56.3
UniProt: O95980 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95980 NP_066934.1 971 106457 Y309 R E L C T K L Y S M S W G N T
Chimpanzee Pan troglodytes XP_520575 971 106469 Y309 R E L C T K L Y S M S W G N T
Rhesus Macaque Macaca mulatta XP_001083599 971 106512 Y309 R E L C T K L Y S M S W G N T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9Z0J1 971 106117 Y309 R E L C T K L Y S M S W G N T
Rat Rattus norvegicus NP_001101424 920 100041 Y309 R E L C T K L Y S M S W G N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521006 935 102603 T284 L C T K L Y S T S W G N T Q S
Chicken Gallus gallus XP_418897 963 105683 Y303 R E L C T K L Y S T S W G S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648733 1071 117775 F402 R R L C N Q I F T S N W W D A
Honey Bee Apis mellifera XP_392031 925 102011 F306 Q D L C W R A F K A D W E S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790172 719 79733 G130 R D T H D G A G N E I S H P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 98.9 N.A. N.A. 92.8 86.9 N.A. 85.7 83.8 N.A. N.A. N.A. 30.6 33.5 N.A. 34
Protein Similarity: 100 99.9 99.2 N.A. N.A. 95.7 90.3 N.A. 91.2 90.8 N.A. N.A. N.A. 48.8 51.5 N.A. 47.9
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 6.6 80 N.A. N.A. N.A. 26.6 20 N.A. 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 93.3 N.A. N.A. N.A. 66.6 60 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 0 0 10 0 0 0 0 10 % A
% Cys: 0 10 0 80 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 10 0 0 0 0 0 10 0 0 10 0 % D
% Glu: 0 60 0 0 0 0 0 0 0 10 0 0 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 10 0 60 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 60 0 0 10 0 0 0 0 0 0 % K
% Leu: 10 0 80 0 10 0 60 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 10 0 10 10 0 50 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % Q
% Arg: 80 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 10 0 70 10 60 10 0 20 30 % S
% Thr: 0 0 20 0 60 0 0 10 10 10 0 0 10 0 50 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 10 0 80 10 0 0 % W
% Tyr: 0 0 0 0 0 10 0 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _