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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MBD3 All Species: 31.52
Human Site: S197 Identified Species: 69.33
UniProt: O95983 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95983 NP_003917.1 291 32844 S197 M P I T G Q L S A A V E K N P
Chimpanzee Pan troglodytes XP_001148653 259 28995 V200 I R K Q E E L V Q Q V R K R L
Rhesus Macaque Macaca mulatta XP_001095979 291 32842 S197 M P I T G Q L S A A V E K N P
Dog Lupus familis XP_854597 291 32827 S197 M P I T G Q L S A A V E K N P
Cat Felis silvestris
Mouse Mus musculus Q9Z2D8 285 32150 S197 L P I T G Q L S A A V E K N P
Rat Rattus norvegicus NP_001102205 286 32279 S197 L P I T G Q L S A A V E K N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507719 302 33422 S207 M P I T G Q L S A A V E K N P
Chicken Gallus gallus NP_001073219 233 26128 R182 L V Q Q V R K R L E E A L M A
Frog Xenopus laevis NP_001081946 303 34060 S217 M P I T G Q L S A A V E K N P
Zebra Danio Brachydanio rerio NP_997934 273 30601 S196 A P I T G Q L S A A V E K N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792656 274 30760 G214 Q P I L G Q V G T Q P H L D K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89 99.3 95.5 N.A. 94.5 94.5 N.A. 80.4 73.5 82.1 78.3 N.A. N.A. N.A. N.A. 49.1
Protein Similarity: 100 89 99.6 98.2 N.A. 97.2 97.5 N.A. 86 76.9 88.7 85.9 N.A. N.A. N.A. N.A. 65.6
P-Site Identity: 100 20 100 100 N.A. 93.3 93.3 N.A. 100 0 100 93.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 100 13.3 100 93.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 73 73 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 10 0 0 0 10 10 73 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 82 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 10 0 82 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 0 0 0 82 0 10 % K
% Leu: 28 0 0 10 0 0 82 0 10 0 0 0 19 0 10 % L
% Met: 46 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 % N
% Pro: 0 82 0 0 0 0 0 0 0 0 10 0 0 0 73 % P
% Gln: 10 0 10 19 0 82 0 0 10 19 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 10 0 10 0 0 0 10 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 73 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 10 0 0 10 0 10 10 0 0 82 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _