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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MBD3
All Species:
24.55
Human Site:
S86
Identified Species:
54
UniProt:
O95983
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95983
NP_003917.1
291
32844
S86
Q
R
V
R
Y
D
S
S
N
Q
V
K
G
K
P
Chimpanzee
Pan troglodytes
XP_001148653
259
28995
T81
S
I
F
K
Q
P
V
T
K
I
T
N
H
P
S
Rhesus Macaque
Macaca mulatta
XP_001095979
291
32842
S86
Q
R
V
R
Y
D
S
S
N
Q
V
K
G
K
P
Dog
Lupus familis
XP_854597
291
32827
S86
Q
R
V
R
Y
D
S
S
N
Q
V
K
G
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2D8
285
32150
S86
Q
R
V
R
Y
D
S
S
N
Q
V
K
G
K
P
Rat
Rattus norvegicus
NP_001102205
286
32279
S86
Q
R
V
R
Y
D
S
S
N
Q
V
K
G
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507719
302
33422
S96
Q
R
M
R
Y
D
C
S
S
Q
A
K
G
K
P
Chicken
Gallus gallus
NP_001073219
233
26128
Q72
N
K
V
K
S
D
P
Q
K
A
V
D
Q
P
R
Frog
Xenopus laevis
NP_001081946
303
34060
L106
Q
R
M
R
Y
D
G
L
N
Q
S
K
G
K
P
Zebra Danio
Brachydanio rerio
NP_997934
273
30601
S86
Q
R
I
R
S
D
H
S
Q
N
K
G
K
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792656
274
30760
D102
R
L
K
N
I
H
F
D
Y
S
R
G
T
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
99.3
95.5
N.A.
94.5
94.5
N.A.
80.4
73.5
82.1
78.3
N.A.
N.A.
N.A.
N.A.
49.1
Protein Similarity:
100
89
99.6
98.2
N.A.
97.2
97.5
N.A.
86
76.9
88.7
85.9
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
73.3
20
73.3
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
86.6
33.3
80
40
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
82
0
10
0
0
0
10
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
19
64
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
10
% H
% Ile:
0
10
10
0
10
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
10
19
0
0
0
0
19
0
10
64
10
73
0
% K
% Leu:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
55
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
0
0
0
0
28
64
% P
% Gln:
73
0
0
0
10
0
0
10
10
64
0
0
10
0
0
% Q
% Arg:
10
73
0
73
0
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
10
0
0
0
19
0
46
64
10
10
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% T
% Val:
0
0
55
0
0
0
10
0
0
0
55
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
64
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _