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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CH25H
All Species:
22.42
Human Site:
S78
Identified Species:
44.85
UniProt:
O95992
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95992
NP_003947.1
272
31745
S78
Y
K
I
H
P
D
F
S
P
S
A
Q
Q
L
L
Chimpanzee
Pan troglodytes
XP_507901
272
31755
S78
Y
K
I
H
P
D
F
S
P
S
A
R
Q
L
L
Rhesus Macaque
Macaca mulatta
XP_001083208
272
31831
S78
Y
K
I
H
P
D
F
S
P
S
A
R
Q
L
L
Dog
Lupus familis
XP_543596
270
30407
G78
Y
K
V
H
P
D
C
G
P
S
A
R
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0F5
298
34654
S78
Y
K
I
H
P
D
F
S
P
S
V
K
Q
L
L
Rat
Rattus norvegicus
Q4QQV7
298
34396
S78
Y
K
I
H
P
D
F
S
P
S
V
R
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509608
304
35019
S112
Y
K
L
N
P
R
A
S
P
S
P
R
Q
M
L
Chicken
Gallus gallus
Q5ZLL6
296
35467
P88
Y
K
I
Q
P
D
K
P
E
T
W
E
K
Q
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5PRC0
251
29716
N78
C
L
A
L
S
L
Y
N
H
V
V
Y
I
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20027
300
36047
K83
A
K
I
Q
K
D
R
K
V
T
W
D
L
I
K
Sea Urchin
Strong. purpuratus
XP_788589
290
34201
H93
Y
K
L
H
Q
D
I
H
M
T
Q
P
Q
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53045
309
36461
Y81
F
I
I
D
Q
I
P
Y
F
R
R
W
K
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.8
70.5
N.A.
71.8
73.4
N.A.
56.5
24.6
N.A.
53.3
N.A.
N.A.
N.A.
30.3
32
Protein Similarity:
100
100
96.3
80.8
N.A.
78.5
79.8
N.A.
68.4
43.9
N.A.
67.2
N.A.
N.A.
N.A.
48.3
49.3
P-Site Identity:
100
93.3
93.3
73.3
N.A.
86.6
86.6
N.A.
53.3
33.3
N.A.
0
N.A.
N.A.
N.A.
20
40
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
80
53.3
N.A.
13.3
N.A.
N.A.
N.A.
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
9
0
0
0
34
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
75
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% E
% Phe:
9
0
0
0
0
0
42
0
9
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
59
0
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
9
67
0
0
9
9
0
0
0
0
0
9
9
0
% I
% Lys:
0
84
0
0
9
0
9
9
0
0
0
9
17
0
9
% K
% Leu:
0
9
17
9
0
9
0
0
0
0
0
0
9
67
59
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
67
0
9
9
59
0
9
9
0
0
9
% P
% Gln:
0
0
0
17
17
0
0
0
0
0
9
9
67
9
9
% Q
% Arg:
0
0
0
0
0
9
9
0
0
9
9
42
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
50
0
59
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
9
9
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
9
% W
% Tyr:
75
0
0
0
0
0
9
9
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _