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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGR2
All Species:
17.27
Human Site:
S45
Identified Species:
38
UniProt:
O95994
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95994
NP_006399.1
175
19979
S45
P
K
L
P
Q
T
L
S
R
G
W
G
D
Q
L
Chimpanzee
Pan troglodytes
XP_001149873
166
19169
Q46
G
D
D
I
T
W
V
Q
T
Y
E
E
G
L
F
Rhesus Macaque
Macaca mulatta
XP_001105285
175
19933
S45
P
K
L
P
Q
T
L
S
R
G
W
G
D
Q
L
Dog
Lupus familis
XP_539450
175
19850
S45
P
K
L
P
Q
T
L
S
R
G
W
G
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
O88312
175
19901
S45
P
K
L
P
Q
T
L
S
R
G
W
G
D
Q
L
Rat
Rattus norvegicus
Q498E0
170
19000
A50
D
G
K
K
E
A
A
A
S
G
L
P
L
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508352
175
20002
S45
T
K
F
P
Q
T
L
S
R
G
W
G
D
N
L
Chicken
Gallus gallus
XP_418698
172
19824
W45
P
Q
T
L
S
R
G
W
G
D
Q
L
I
W
T
Frog
Xenopus laevis
Q7ZZH4
164
18665
Q45
G
D
N
L
E
W
V
Q
T
Y
E
E
G
L
Y
Zebra Danio
Brachydanio rerio
Q5RZ65
171
19658
D45
T
L
S
R
G
W
G
D
Q
L
I
W
A
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791682
161
17742
K46
E
D
G
L
K
L
A
K
E
N
N
K
P
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.8
98.8
95.4
N.A.
91.4
34.2
N.A.
82.2
78.2
64
71.4
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
100
80.5
99.4
97.1
N.A.
96
52
N.A.
92
89.7
77.1
84
N.A.
N.A.
N.A.
N.A.
53.7
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
80
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
100
100
N.A.
100
26.6
N.A.
80
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
19
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
28
10
0
0
0
0
10
0
10
0
0
46
0
0
% D
% Glu:
10
0
0
0
19
0
0
0
10
0
19
19
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
19
10
10
0
10
0
19
0
10
55
0
46
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
46
10
10
10
0
0
10
0
0
0
10
0
0
0
% K
% Leu:
0
10
37
28
0
10
46
0
0
10
10
10
10
19
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
10
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
10
0
0
10
0
% N
% Pro:
46
0
0
46
0
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
10
0
0
46
0
0
19
10
0
10
0
0
46
0
% Q
% Arg:
0
0
0
10
0
10
0
0
46
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
46
10
0
0
0
0
0
0
% S
% Thr:
19
0
10
0
10
46
0
0
19
0
0
0
0
0
19
% T
% Val:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
28
0
10
0
0
46
10
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _