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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGR2
All Species:
35.76
Human Site:
Y124
Identified Species:
78.67
UniProt:
O95994
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95994
NP_006399.1
175
19979
Y124
H
L
S
P
D
G
Q
Y
V
P
R
I
M
F
V
Chimpanzee
Pan troglodytes
XP_001149873
166
19169
Y115
N
L
S
P
D
G
Q
Y
V
P
R
I
M
F
V
Rhesus Macaque
Macaca mulatta
XP_001105285
175
19933
Y124
H
L
S
P
D
G
Q
Y
V
P
R
I
L
F
V
Dog
Lupus familis
XP_539450
175
19850
Y124
H
L
S
P
D
G
Q
Y
V
P
R
I
I
F
V
Cat
Felis silvestris
Mouse
Mus musculus
O88312
175
19901
Y124
H
L
S
P
D
G
Q
Y
V
P
R
I
V
F
V
Rat
Rattus norvegicus
Q498E0
170
19000
G120
I
L
F
L
D
P
S
G
K
V
R
P
E
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508352
175
20002
Y124
H
L
S
P
D
G
Q
Y
V
P
R
I
M
F
I
Chicken
Gallus gallus
XP_418698
172
19824
Y121
N
L
A
P
D
G
Q
Y
V
P
R
I
L
F
I
Frog
Xenopus laevis
Q7ZZH4
164
18665
Y113
N
L
Q
L
D
G
Q
Y
V
P
K
I
I
F
V
Zebra Danio
Brachydanio rerio
Q5RZ65
171
19658
Y120
H
L
S
P
D
G
Q
Y
V
P
R
I
I
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791682
161
17742
F112
G
Y
I
P
R
I
L
F
L
N
S
D
G
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.8
98.8
95.4
N.A.
91.4
34.2
N.A.
82.2
78.2
64
71.4
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
100
80.5
99.4
97.1
N.A.
96
52
N.A.
92
89.7
77.1
84
N.A.
N.A.
N.A.
N.A.
53.7
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
20
N.A.
93.3
73.3
66.6
93.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
100
86.6
100
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
91
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
10
0
0
0
0
0
82
0
% F
% Gly:
10
0
0
0
0
82
0
10
0
0
0
0
10
0
0
% G
% His:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
10
0
0
0
0
0
82
28
10
28
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% K
% Leu:
0
91
0
19
0
0
10
0
10
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% M
% Asn:
28
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
82
0
10
0
0
0
82
0
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
82
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
82
0
0
0
0
% R
% Ser:
0
0
64
0
0
0
10
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
82
10
0
0
10
10
73
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _