KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
6.06
Human Site:
S1592
Identified Species:
12.12
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
S1592
S
L
S
E
P
E
P
S
E
P
P
A
V
H
P
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
Y1971
S
K
P
Q
A
S
G
Y
A
P
K
S
F
H
V
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
P1594
S
L
S
E
P
E
P
P
E
P
P
S
V
S
P
Dog
Lupus familis
XP_542202
2539
269675
P1840
S
L
S
E
P
D
P
P
A
H
P
P
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
S1562
Y
S
L
T
S
S
A
S
S
L
S
E
P
E
A
Rat
Rattus norvegicus
P70478
2842
310514
Y2006
G
K
P
Q
A
S
G
Y
A
P
K
S
F
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
Y2008
S
R
P
Q
A
S
G
Y
A
P
K
S
F
H
V
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
P1999
T
Q
L
G
L
R
R
P
Q
T
S
G
Y
A
P
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
S1424
E
D
M
E
D
Q
Y
S
E
G
N
S
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
N1561
P
S
S
H
I
L
P
N
P
I
D
A
I
A
T
Honey Bee
Apis mellifera
XP_624558
2760
306907
Q1990
N
Q
D
Q
N
N
Q
Q
E
I
N
T
I
C
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
D1942
P
L
S
Y
A
V
E
D
T
P
T
C
F
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
20
80
46.6
N.A.
6.6
13.3
N.A.
20
N.A.
6.6
20
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
33.3
86.6
53.3
N.A.
6.6
26.6
N.A.
33.3
N.A.
20
33.3
N.A.
33.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
9
0
34
0
0
17
9
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% C
% Asp:
0
9
9
0
9
9
0
9
0
0
9
0
9
9
9
% D
% Glu:
9
0
0
34
0
17
9
0
34
0
0
9
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% F
% Gly:
9
0
0
9
0
0
25
0
0
9
0
9
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
0
0
0
34
9
% H
% Ile:
0
0
0
0
9
0
0
0
0
17
0
0
17
0
0
% I
% Lys:
0
17
0
0
0
0
0
0
0
0
25
0
0
0
0
% K
% Leu:
0
34
17
0
9
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
9
0
9
0
0
17
0
0
0
0
% N
% Pro:
17
0
25
0
25
0
34
25
9
50
25
9
9
0
25
% P
% Gln:
0
17
0
34
0
9
9
9
9
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
9
9
0
0
0
0
0
0
9
0
% R
% Ser:
42
17
42
0
9
34
0
25
9
0
17
42
0
17
0
% S
% Thr:
9
0
0
9
0
0
0
0
9
9
9
9
0
0
9
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
17
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
9
25
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _