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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APC2 All Species: 13.64
Human Site: T2211 Identified Species: 27.27
UniProt: O95996 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95996 NP_005874.1 2303 243949 T2211 S T S P S L E T R E P P G A P
Chimpanzee Pan troglodytes XP_001143729 2807 307641 G2641 R S G R S P T G N T P P V I D
Rhesus Macaque Macaca mulatta XP_001095216 2303 243755 S2211 S T S P S L E S R E P P G A P
Dog Lupus familis XP_542202 2539 269675 S2448 S T S P S L E S R G P P Q A P
Cat Felis silvestris
Mouse Mus musculus Q9Z1K7 2274 243121 S2181 S T S P S L E S R D P P Q A P
Rat Rattus norvegicus P70478 2842 310514 E2662 E D V W V R I E D C P I N N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511806 2844 309621 E2663 E D V W V R I E D C P I N N P
Chicken Gallus gallus
Frog Xenopus laevis P70039 2829 310863 E2656 E D V W V R I E D C P I N N P
Zebra Danio Brachydanio rerio XP_694133 2091 233440 S2003 E K V A S A P S S P P D R R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477152 2417 261266 K2265 R A S K L P T K K G T A S G G
Honey Bee Apis mellifera XP_624558 2760 306907 I2633 Y K K D T I D I G D A S V V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783363 3212 346162 L2794 R H S S S Y S L S S I S T N H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.2 96.4 72.6 N.A. 81.1 34.7 N.A. 35.9 N.A. 34.4 36 N.A. 24.2 22.7 N.A. 25
Protein Similarity: 100 50.4 97.3 76.1 N.A. 85.6 49.8 N.A. 49.9 N.A. 48.7 49.9 N.A. 39 38.1 N.A. 40
P-Site Identity: 100 20 93.3 80 N.A. 80 13.3 N.A. 13.3 N.A. 13.3 13.3 N.A. 6.6 0 N.A. 13.3
P-Site Similarity: 100 26.6 100 86.6 N.A. 93.3 13.3 N.A. 13.3 N.A. 13.3 20 N.A. 13.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 9 0 0 0 0 9 9 0 34 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 % C
% Asp: 0 25 0 9 0 0 9 0 25 17 0 9 0 0 9 % D
% Glu: 34 0 0 0 0 0 34 25 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 9 9 17 0 0 17 9 17 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 9 25 9 0 0 9 25 0 9 0 % I
% Lys: 0 17 9 9 0 0 0 9 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 34 0 9 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 25 34 0 % N
% Pro: 0 0 0 34 0 17 9 0 0 9 75 42 0 0 59 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Q
% Arg: 25 0 0 9 0 25 0 0 34 0 0 0 9 9 0 % R
% Ser: 34 9 50 9 59 0 9 34 17 9 0 17 9 0 0 % S
% Thr: 0 34 0 0 9 0 17 9 0 9 9 0 9 0 0 % T
% Val: 0 0 34 0 25 0 0 0 0 0 0 0 17 9 0 % V
% Trp: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _