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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC2
All Species:
4.55
Human Site:
Y1510
Identified Species:
9.09
UniProt:
O95996
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95996
NP_005874.1
2303
243949
Y1510
E
E
A
V
Y
C
F
Y
G
N
D
S
D
E
E
Chimpanzee
Pan troglodytes
XP_001143729
2807
307641
I1889
N
R
G
Q
P
K
P
I
L
Q
K
Q
S
T
F
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
Y1512
E
E
A
V
Y
C
F
Y
G
N
D
S
D
E
E
Dog
Lupus familis
XP_542202
2539
269675
E1758
L
C
L
T
T
P
T
E
E
A
V
Y
C
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K7
2274
243121
L1480
G
D
G
A
L
Q
S
L
C
L
T
T
P
T
E
Rat
Rattus norvegicus
P70478
2842
310514
L1924
N
R
G
P
S
K
P
L
L
Q
E
Q
P
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1926
S
R
G
Q
P
K
T
S
L
Q
K
P
A
A
F
Chicken
Gallus gallus
Frog
Xenopus laevis
P70039
2829
310863
R1917
G
P
K
S
L
G
G
R
D
Q
P
K
A
L
V
Zebra Danio
Brachydanio rerio
XP_694133
2091
233440
R1342
S
Q
W
E
S
S
L
R
K
F
M
E
I
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
R1479
H
H
H
R
E
R
E
R
E
R
K
D
E
K
L
Honey Bee
Apis mellifera
XP_624558
2760
306907
H1908
S
T
P
R
K
R
L
H
K
N
L
T
P
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
D1860
K
S
A
M
S
P
L
D
S
P
R
V
F
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.2
96.4
72.6
N.A.
81.1
34.7
N.A.
35.9
N.A.
34.4
36
N.A.
24.2
22.7
N.A.
25
Protein Similarity:
100
50.4
97.3
76.1
N.A.
85.6
49.8
N.A.
49.9
N.A.
48.7
49.9
N.A.
39
38.1
N.A.
40
P-Site Identity:
100
0
100
0
N.A.
6.6
0
N.A.
0
N.A.
0
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
0
100
0
N.A.
20
6.6
N.A.
0
N.A.
0
13.3
N.A.
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
9
0
0
0
0
0
9
0
0
17
25
0
% A
% Cys:
0
9
0
0
0
17
0
0
9
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
9
0
17
9
17
0
9
% D
% Glu:
17
17
0
9
9
0
9
9
17
0
9
9
9
17
25
% E
% Phe:
0
0
0
0
0
0
17
0
0
9
0
0
9
9
25
% F
% Gly:
17
0
34
0
0
9
9
0
17
0
0
0
0
0
0
% G
% His:
9
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
9
0
9
0
9
25
0
0
17
0
25
9
0
17
0
% K
% Leu:
9
0
9
0
17
0
25
17
25
9
9
0
0
9
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% N
% Pro:
0
9
9
9
17
17
17
0
0
9
9
9
25
0
0
% P
% Gln:
0
9
0
17
0
9
0
0
0
34
0
17
0
0
9
% Q
% Arg:
0
25
0
17
0
17
0
25
0
9
9
0
0
0
0
% R
% Ser:
25
9
0
9
25
9
9
9
9
0
0
17
9
0
0
% S
% Thr:
0
9
0
9
9
0
17
0
0
0
9
17
0
25
0
% T
% Val:
0
0
0
17
0
0
0
0
0
0
9
9
0
0
17
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
17
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _