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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPTM1
All Species:
21.52
Human Site:
S456
Identified Species:
43.03
UniProt:
O96005
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96005
NP_001285.1
669
76097
S456
A
G
I
F
P
R
L
S
F
K
D
K
S
T
Y
Chimpanzee
Pan troglodytes
XP_001162487
669
76076
S456
A
G
I
F
P
R
L
S
F
K
D
K
S
T
Y
Rhesus Macaque
Macaca mulatta
XP_001102772
669
76092
S456
A
G
I
F
P
R
L
S
F
K
D
K
S
T
Y
Dog
Lupus familis
XP_541570
673
76142
T456
A
G
L
F
P
R
P
T
F
K
D
K
S
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBZ3
664
75272
T456
A
G
I
F
P
C
P
T
F
K
D
K
S
T
Y
Rat
Rattus norvegicus
NP_001099702
664
75258
T456
A
G
I
F
P
C
P
T
F
R
D
K
S
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKJ0
536
61630
T333
V
L
W
R
C
F
S
T
V
V
I
F
L
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DEL2
631
72880
L426
V
S
V
F
I
G
L
L
I
D
F
W
K
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608819
641
73582
H435
G
I
E
V
W
K
I
H
K
V
V
D
I
N
Y
Honey Bee
Apis mellifera
XP_001122740
644
75800
A438
T
V
V
R
I
S
C
A
I
G
L
C
I
E
V
Nematode Worm
Caenorhab. elegans
NP_509196
602
69521
I399
S
V
G
A
G
L
L
I
E
C
W
K
I
P
K
Sea Urchin
Strong. purpuratus
XP_787952
543
61966
G340
N
E
D
E
E
E
D
G
L
K
R
A
I
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
96.4
N.A.
95
94.7
N.A.
N.A.
30.3
N.A.
74.2
N.A.
50.6
51.1
49.6
48.4
Protein Similarity:
100
99.8
99.6
97.3
N.A.
96.8
96.5
N.A.
N.A.
48.4
N.A.
83.7
N.A.
66.6
68.4
64.2
60.9
P-Site Identity:
100
100
100
80
N.A.
80
73.3
N.A.
N.A.
0
N.A.
13.3
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
20
N.A.
20
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
9
17
9
0
0
9
0
9
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
0
0
9
50
9
0
0
0
% D
% Glu:
0
9
9
9
9
9
0
0
9
0
0
0
0
9
9
% E
% Phe:
0
0
0
59
0
9
0
0
50
0
9
9
0
9
0
% F
% Gly:
9
50
9
0
9
9
0
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
42
0
17
0
9
9
17
0
9
0
34
9
0
% I
% Lys:
0
0
0
0
0
9
0
0
9
50
0
59
9
0
9
% K
% Leu:
0
9
9
0
0
9
42
9
9
0
9
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
50
0
25
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
34
0
0
0
9
9
0
0
0
0
% R
% Ser:
9
9
0
0
0
9
9
25
0
0
0
0
50
0
0
% S
% Thr:
9
0
0
0
0
0
0
34
0
0
0
0
0
50
9
% T
% Val:
17
17
17
9
0
0
0
0
9
17
9
0
0
0
9
% V
% Trp:
0
0
9
0
9
0
0
0
0
0
9
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _