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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPTM1
All Species:
13.03
Human Site:
T646
Identified Species:
26.06
UniProt:
O96005
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96005
NP_001285.1
669
76097
T646
T
S
L
P
T
K
P
T
Q
G
A
S
S
A
S
Chimpanzee
Pan troglodytes
XP_001162487
669
76076
T646
T
S
L
P
T
K
P
T
Q
G
A
S
S
A
S
Rhesus Macaque
Macaca mulatta
XP_001102772
669
76092
T646
T
S
L
P
T
K
P
T
Q
G
A
S
S
A
T
Dog
Lupus familis
XP_541570
673
76142
P646
E
E
A
S
T
P
L
P
A
K
P
T
Q
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBZ3
664
75272
T646
K
A
T
S
G
A
C
T
A
S
Q
P
Q
E
A
Rat
Rattus norvegicus
NP_001099702
664
75258
T646
T
A
T
P
G
A
C
T
A
S
Q
P
Q
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKJ0
536
61630
E522
V
D
K
S
R
V
N
E
Y
G
E
S
Y
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DEL2
631
72880
E615
S
A
Q
P
A
A
G
E
T
P
A
A
I
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608819
641
73582
P625
A
N
G
A
I
E
G
P
Q
A
A
P
A
I
K
Honey Bee
Apis mellifera
XP_001122740
644
75800
Q628
K
I
T
K
D
K
K
Q
E
F
I
K
D
R
A
Nematode Worm
Caenorhab. elegans
NP_509196
602
69521
A588
P
V
E
G
T
E
T
A
K
S
D
T
P
A
I
Sea Urchin
Strong. purpuratus
XP_787952
543
61966
S529
V
N
G
G
A
T
P
S
I
E
A
A
D
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
96.4
N.A.
95
94.7
N.A.
N.A.
30.3
N.A.
74.2
N.A.
50.6
51.1
49.6
48.4
Protein Similarity:
100
99.8
99.6
97.3
N.A.
96.8
96.5
N.A.
N.A.
48.4
N.A.
83.7
N.A.
66.6
68.4
64.2
60.9
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
20
N.A.
N.A.
13.3
N.A.
13.3
N.A.
13.3
6.6
13.3
20
P-Site Similarity:
100
100
100
20
N.A.
20
26.6
N.A.
N.A.
13.3
N.A.
33.3
N.A.
33.3
20
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
9
9
17
25
0
9
25
9
50
17
9
34
25
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
0
9
0
17
0
9
% D
% Glu:
9
9
9
0
0
17
0
17
9
9
9
0
0
25
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
17
17
17
0
17
0
0
34
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
0
9
0
9
0
9
9
9
% I
% Lys:
17
0
9
9
0
34
9
0
9
9
0
9
0
9
9
% K
% Leu:
0
0
25
0
0
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
42
0
9
34
17
0
9
9
25
9
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
34
0
17
0
25
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
25
0
25
0
0
0
9
0
25
0
34
25
0
25
% S
% Thr:
34
0
25
0
42
9
9
42
9
0
0
17
0
9
9
% T
% Val:
17
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _