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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPTM1
All Species:
23.94
Human Site:
Y280
Identified Species:
47.88
UniProt:
O96005
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96005
NP_001285.1
669
76097
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Chimpanzee
Pan troglodytes
XP_001162487
669
76076
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Rhesus Macaque
Macaca mulatta
XP_001102772
669
76092
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Dog
Lupus familis
XP_541570
673
76142
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBZ3
664
75272
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Rat
Rattus norvegicus
NP_001099702
664
75258
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKJ0
536
61630
D164
E
K
Q
T
S
A
L
D
E
P
V
S
H
W
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DEL2
631
72880
V256
T
A
W
V
K
G
S
V
P
P
P
L
D
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608819
641
73582
V260
P
P
P
L
D
D
Y
V
K
F
V
D
G
G
K
Honey Bee
Apis mellifera
XP_001122740
644
75800
T261
N
L
T
I
N
L
V
T
D
H
T
N
W
V
Y
Nematode Worm
Caenorhab. elegans
NP_509196
602
69521
G230
D
H
S
Q
W
Q
K
G
A
I
P
P
P
L
D
Sea Urchin
Strong. purpuratus
XP_787952
543
61966
G171
H
V
F
F
T
K
S
G
Y
S
P
D
P
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
96.4
N.A.
95
94.7
N.A.
N.A.
30.3
N.A.
74.2
N.A.
50.6
51.1
49.6
48.4
Protein Similarity:
100
99.8
99.6
97.3
N.A.
96.8
96.5
N.A.
N.A.
48.4
N.A.
83.7
N.A.
66.6
68.4
64.2
60.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
N.A.
0
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
6.6
N.A.
0
26.6
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
50
0
0
9
9
0
9
9
0
50
17
9
0
9
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
0
0
0
0
50
9
0
0
0
0
0
% F
% Gly:
50
0
0
0
0
9
0
17
0
0
0
0
9
9
0
% G
% His:
9
9
0
0
0
0
0
0
0
9
0
0
9
0
9
% H
% Ile:
0
0
0
9
0
50
50
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
9
9
0
9
0
0
0
0
0
9
% K
% Leu:
0
9
0
9
0
9
9
0
0
0
0
9
0
9
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
0
0
0
50
0
9
0
50
0
% N
% Pro:
9
9
9
0
50
0
0
0
9
17
25
9
17
0
0
% P
% Gln:
0
0
9
9
0
9
0
0
0
0
0
0
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% R
% Ser:
0
0
9
0
9
0
17
0
0
9
0
9
0
0
0
% S
% Thr:
9
0
9
9
9
0
0
9
0
0
9
0
0
0
0
% T
% Val:
0
9
0
9
0
0
9
17
0
0
17
0
0
9
0
% V
% Trp:
0
0
9
0
9
0
0
0
0
0
0
0
59
9
0
% W
% Tyr:
0
0
50
50
0
0
9
50
9
0
0
50
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _