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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TOMM40 All Species: 24.24
Human Site: T246 Identified Species: 48.48
UniProt: O96008 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O96008 NP_001122388.1 361 37893 T246 R R P G E E G T V M S L A G K
Chimpanzee Pan troglodytes XP_001149548 496 53468 T246 Q Q P G E E G T V M S L A G K
Rhesus Macaque Macaca mulatta XP_001109661 361 37799 T246 R R P G E E G T V M S L A G K
Dog Lupus familis XP_852633 361 37650 T246 R R P G E E G T V M S L A G K
Cat Felis silvestris
Mouse Mus musculus Q9QYA2 361 37877 T246 R R P G E E G T V M S L A G K
Rat Rattus norvegicus Q75Q40 361 37901 T246 R R P G E K G T V M S L A G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q7ZTM6 336 36111 R228 T V M S L A G R Y T A P S W T
Zebra Danio Brachydanio rerio NP_955908 344 36190 V234 E G T V T S L V G R Y T G S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U4L6 344 36318 S232 G R Q I A I M S V V G R Y T A
Honey Bee Apis mellifera XP_391836 332 35279 R224 A V L S A A G R Y T N G D S T
Nematode Worm Caenorhab. elegans Q18090 301 32367 Y193 V L S Y A A R Y T A N H F I A
Sea Urchin Strong. purpuratus XP_790832 330 35324 G222 A A V V S L A G K Y A A D N W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.7 99.1 96.4 N.A. 93 91.6 N.A. N.A. N.A. 76.7 71.4 N.A. 52.6 52 37.1 50.4
Protein Similarity: 100 66.5 99.4 97.5 N.A. 95.5 94.7 N.A. N.A. N.A. 83.9 82.2 N.A. 66.1 67.5 52 67
P-Site Identity: 100 86.6 100 100 N.A. 100 93.3 N.A. N.A. N.A. 6.6 0 N.A. 13.3 6.6 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 20 0 N.A. 26.6 13.3 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 25 25 9 0 0 9 17 9 50 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % D
% Glu: 9 0 0 0 50 42 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 9 9 0 50 0 0 67 9 9 0 9 9 9 50 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 9 0 9 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 50 % K
% Leu: 0 9 9 0 9 9 9 0 0 0 0 50 0 0 0 % L
% Met: 0 0 9 0 0 0 9 0 0 50 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 17 0 0 9 9 % N
% Pro: 0 0 50 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 9 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 42 50 0 0 0 0 9 17 0 9 0 9 0 0 0 % R
% Ser: 0 0 9 17 9 9 0 9 0 0 50 0 9 17 0 % S
% Thr: 9 0 9 0 9 0 0 50 9 17 0 9 0 9 17 % T
% Val: 9 17 9 17 0 0 0 9 59 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % W
% Tyr: 0 0 0 9 0 0 0 9 17 9 9 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _