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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAPSA All Species: 38.79
Human Site: S129 Identified Species: 65.64
UniProt: O96009 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O96009 NP_004842.1 420 45387 S129 F D P K A S S S F Q A N G T K
Chimpanzee Pan troglodytes XP_524345 420 45392 S129 F D P K A S S S F Q A N G T K
Rhesus Macaque Macaca mulatta Q6DLW5 406 44943 S137 F D A S D S S S Y K H N G T E
Dog Lupus familis XP_533610 422 44982 S127 Y N S K A S S S F Q P N G T K
Cat Felis silvestris
Mouse Mus musculus O09043 419 45526 S124 F N P K A S S S F R P N G T K
Rat Rattus norvegicus P24268 407 44662 T130 Y N S D K S S T Y V K N G T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q05744 398 43280 T129 Y D A S K S S T Y V E N G T E
Frog Xenopus laevis Q805F2 397 42983 E125 P Q L S S T Y E S N G N N F S
Zebra Danio Brachydanio rerio NP_571785 399 43486 T126 Y N G G K S S T Y V K N G T Q
Tiger Blowfish Takifugu rubipres NP_001072052 396 43134 S127 Y N S A K S S S Y V K N G T A
Fruit Fly Dros. melanogaster NP_652013 392 42454 T124 Y D A S K S K T Y T K N G T E
Honey Bee Apis mellifera XP_392857 385 42204 T116 Y D N T K S S T Y K K N G T D
Nematode Worm Caenorhab. elegans P55956 398 43395 S120 F D C K K S S S C T A T G A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q01294 396 42914 T134 Y E S S E S S T Y K K N G T S
Conservation
Percent
Protein Identity: 100 98.5 41.1 78.1 N.A. 71.4 48 N.A. N.A. 50 42.1 46.1 46.9 46.4 45.4 40 N.A.
Protein Similarity: 100 99.2 55.9 85 N.A. 80 64.7 N.A. N.A. 63.8 58.5 61.1 62.8 60.9 61.6 55.7 N.A.
P-Site Identity: 100 100 53.3 73.3 N.A. 80 33.3 N.A. N.A. 40 6.6 33.3 40 33.3 40 53.3 N.A.
P-Site Similarity: 100 100 73.3 86.6 N.A. 93.3 60 N.A. N.A. 66.6 20 66.6 60 60 66.6 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 37.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 55
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 8 29 0 0 0 0 0 22 0 0 8 8 % A
% Cys: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 50 0 8 8 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 8 0 0 8 0 0 8 0 0 8 0 0 0 22 % E
% Phe: 36 0 0 0 0 0 0 0 29 0 0 0 0 8 0 % F
% Gly: 0 0 8 8 0 0 0 0 0 0 8 0 93 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 36 50 0 8 0 0 22 43 0 0 0 29 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 36 8 0 0 0 0 0 0 8 0 93 8 0 0 % N
% Pro: 8 0 22 0 0 0 0 0 0 0 15 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 22 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 29 36 8 93 86 50 8 0 0 0 0 0 29 % S
% Thr: 0 0 0 8 0 8 0 43 0 15 0 8 0 86 0 % T
% Val: 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 58 0 0 0 0 0 8 0 58 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _