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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAPSA All Species: 17.27
Human Site: S218 Identified Species: 29.23
UniProt: O96009 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O96009 NP_004842.1 420 45387 S218 L L D K P V F S F Y L N R D P
Chimpanzee Pan troglodytes XP_524345 420 45392 S218 L L D K P V F S F Y L N R D P
Rhesus Macaque Macaca mulatta Q6DLW5 406 44943 K220 I L S Q G V L K E D V F S F Y
Dog Lupus familis XP_533610 422 44982 S216 L L D K P V F S F Y L N R D P
Cat Felis silvestris
Mouse Mus musculus O09043 419 45526 S213 L L E K P V F S F Y L N R D S
Rat Rattus norvegicus P24268 407 44662 D211 N K V L P V F D N L M K Q K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q05744 398 43280 N205 K V T P F F D N V M Q Q K L I
Frog Xenopus laevis Q805F2 397 42983 E207 M I A Q N L V E L P M F S V Y
Zebra Danio Brachydanio rerio NP_571785 399 43486 S215 K V E K N V F S F Y L N R N P
Tiger Blowfish Takifugu rubipres NP_001072052 396 43134 N203 G V T P V F D N I M S Q K K V
Fruit Fly Dros. melanogaster NP_652013 392 42454 A200 K V K P P F Y A M Y E Q G L I
Honey Bee Apis mellifera XP_392857 385 42204 N192 G V T P V F Y N M V K Q G L V
Nematode Worm Caenorhab. elegans P55956 398 43395 Q200 K I S Q P M D Q I F A N S A I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q01294 396 42914 K210 G I T P P F Y K M V E Q K L V
Conservation
Percent
Protein Identity: 100 98.5 41.1 78.1 N.A. 71.4 48 N.A. N.A. 50 42.1 46.1 46.9 46.4 45.4 40 N.A.
Protein Similarity: 100 99.2 55.9 85 N.A. 80 64.7 N.A. N.A. 63.8 58.5 61.1 62.8 60.9 61.6 55.7 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 86.6 20 N.A. N.A. 0 0 66.6 0 13.3 0 13.3 N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 93.3 33.3 N.A. N.A. 20 33.3 86.6 20 33.3 20 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 37.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 55
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 0 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 22 0 0 0 22 8 0 8 0 0 0 29 0 % D
% Glu: 0 0 15 0 0 0 0 8 8 0 15 0 0 0 0 % E
% Phe: 0 0 0 0 8 36 43 0 36 8 0 15 0 8 0 % F
% Gly: 22 0 0 0 8 0 0 0 0 0 0 0 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 22 0 0 0 0 0 0 15 0 0 0 0 0 22 % I
% Lys: 29 8 8 36 0 0 0 15 0 0 8 8 22 15 0 % K
% Leu: 29 36 0 8 0 8 8 0 8 8 36 0 0 29 8 % L
% Met: 8 0 0 0 0 8 0 0 22 15 15 0 0 0 0 % M
% Asn: 8 0 0 0 15 0 0 22 8 0 0 43 0 8 0 % N
% Pro: 0 0 0 36 58 0 0 0 0 8 0 0 0 0 29 % P
% Gln: 0 0 0 22 0 0 0 8 0 0 8 36 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 % R
% Ser: 0 0 15 0 0 0 0 36 0 0 8 0 22 0 8 % S
% Thr: 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 36 8 0 15 50 8 0 8 15 8 0 0 8 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 22 0 0 43 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _