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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAPSA All Species: 17.88
Human Site: Y220 Identified Species: 30.26
UniProt: O96009 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O96009 NP_004842.1 420 45387 Y220 D K P V F S F Y L N R D P E E
Chimpanzee Pan troglodytes XP_524345 420 45392 Y220 D K P V F S F Y L N R D P E E
Rhesus Macaque Macaca mulatta Q6DLW5 406 44943 D222 S Q G V L K E D V F S F Y Y N
Dog Lupus familis XP_533610 422 44982 Y218 D K P V F S F Y L N R D P E A
Cat Felis silvestris
Mouse Mus musculus O09043 419 45526 Y215 E K P V F S F Y L N R D S E G
Rat Rattus norvegicus P24268 407 44662 L213 V L P V F D N L M K Q K L V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q05744 398 43280 M207 T P F F D N V M Q Q K L I E K
Frog Xenopus laevis Q805F2 397 42983 P209 A Q N L V E L P M F S V Y M S
Zebra Danio Brachydanio rerio NP_571785 399 43486 Y217 E K N V F S F Y L N R N P D T
Tiger Blowfish Takifugu rubipres NP_001072052 396 43134 M205 T P V F D N I M S Q K K V E K
Fruit Fly Dros. melanogaster NP_652013 392 42454 Y202 K P P F Y A M Y E Q G L I S A
Honey Bee Apis mellifera XP_392857 385 42204 V194 T P V F Y N M V K Q G L V P Q
Nematode Worm Caenorhab. elegans P55956 398 43395 F202 S Q P M D Q I F A N S A I C K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q01294 396 42914 V212 T P P F Y K M V E Q K L V D E
Conservation
Percent
Protein Identity: 100 98.5 41.1 78.1 N.A. 71.4 48 N.A. N.A. 50 42.1 46.1 46.9 46.4 45.4 40 N.A.
Protein Similarity: 100 99.2 55.9 85 N.A. 80 64.7 N.A. N.A. 63.8 58.5 61.1 62.8 60.9 61.6 55.7 N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 80 26.6 N.A. N.A. 6.6 0 66.6 6.6 13.3 0 13.3 N.A.
P-Site Similarity: 100 100 20 93.3 N.A. 86.6 40 N.A. N.A. 26.6 20 86.6 26.6 26.6 20 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 37.8
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 55
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 0 0 8 0 0 8 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 22 0 0 0 22 8 0 8 0 0 0 29 0 15 0 % D
% Glu: 15 0 0 0 0 8 8 0 15 0 0 0 0 43 29 % E
% Phe: 0 0 8 36 43 0 36 8 0 15 0 8 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 15 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 0 0 22 0 0 % I
% Lys: 8 36 0 0 0 15 0 0 8 8 22 15 0 0 22 % K
% Leu: 0 8 0 8 8 0 8 8 36 0 0 29 8 0 0 % L
% Met: 0 0 0 8 0 0 22 15 15 0 0 0 0 8 0 % M
% Asn: 0 0 15 0 0 22 8 0 0 43 0 8 0 0 8 % N
% Pro: 0 36 58 0 0 0 0 8 0 0 0 0 29 8 0 % P
% Gln: 0 22 0 0 0 8 0 0 8 36 8 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 % R
% Ser: 15 0 0 0 0 36 0 0 8 0 22 0 8 8 8 % S
% Thr: 29 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 8 0 15 50 8 0 8 15 8 0 0 8 22 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 22 0 0 43 0 0 0 0 15 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _