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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
16.06
Human Site:
S134
Identified Species:
25.24
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
S134
G
G
P
G
K
A
G
S
R
G
R
F
A
G
H
Chimpanzee
Pan troglodytes
XP_525261
777
87548
S281
K
W
E
Y
Q
R
A
S
S
S
S
P
L
D
Y
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
S134
G
G
P
G
K
A
G
S
Q
G
R
I
A
S
H
Dog
Lupus familis
XP_541627
592
64165
S134
G
A
P
E
K
A
G
S
Q
G
R
A
A
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
S134
M
A
P
D
K
A
G
S
R
A
R
A
T
G
H
Rat
Rattus norvegicus
Q62829
544
60692
S128
D
V
L
K
F
Y
D
S
K
E
T
V
N
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
T244
T
P
S
R
T
A
G
T
S
E
C
S
K
E
S
Chicken
Gallus gallus
XP_001233796
504
55780
E94
G
E
P
D
R
G
K
E
R
P
R
E
R
D
P
Frog
Xenopus laevis
NP_001082100
650
73749
K178
P
P
P
P
D
Y
P
K
D
I
P
E
K
R
G
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
R192
T
P
G
Q
H
R
E
R
E
R
D
R
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
A179
G
T
P
G
V
G
G
A
S
S
G
G
F
K
P
Honey Bee
Apis mellifera
XP_001122147
624
70155
T148
T
N
Q
I
Q
S
Y
T
T
N
F
G
K
Q
H
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
S128
K
Y
Y
T
Q
G
E
S
S
G
Q
K
W
L
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S250
P
S
K
P
E
A
K
S
K
P
V
S
V
K
K
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
P467
E
N
P
R
A
P
P
P
V
P
K
G
P
G
P
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
6.6
80
66.6
N.A.
60
6.6
N.A.
13.3
26.6
6.6
0
N.A.
26.6
6.6
13.3
N.A.
P-Site Similarity:
100
20
86.6
73.3
N.A.
60
13.3
N.A.
20
33.3
6.6
0
N.A.
33.3
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
7
40
7
7
0
7
0
14
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
0
14
7
0
7
0
7
0
7
0
0
14
0
% D
% Glu:
7
7
7
7
7
0
14
7
7
14
0
14
7
7
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
7
7
7
0
0
% F
% Gly:
34
14
7
20
0
20
40
0
0
27
7
20
0
27
7
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
27
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
0
7
0
0
0
% I
% Lys:
14
0
7
7
27
0
14
7
14
0
7
7
20
14
7
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
0
7
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
0
0
0
0
0
0
0
7
0
0
7
7
0
% N
% Pro:
14
20
54
14
0
7
14
7
0
20
7
7
7
0
20
% P
% Gln:
0
0
7
7
20
0
0
0
14
0
7
0
0
7
14
% Q
% Arg:
0
0
0
14
7
14
0
7
20
7
34
7
7
14
7
% R
% Ser:
0
7
7
0
0
7
0
54
27
14
7
14
0
7
7
% S
% Thr:
20
7
0
7
7
0
0
14
7
0
7
0
7
0
0
% T
% Val:
0
7
0
0
7
0
0
0
7
0
7
7
7
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
7
7
0
14
7
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _