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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
16.06
Human Site:
S148
Identified Species:
25.24
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
S148
H
S
E
A
G
G
G
S
G
D
R
R
R
A
G
Chimpanzee
Pan troglodytes
XP_525261
777
87548
S295
Y
S
F
Q
F
T
P
S
R
T
A
G
T
S
G
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
S148
H
S
E
A
G
G
G
S
G
D
R
R
R
V
G
Dog
Lupus familis
XP_541627
592
64165
S148
R
S
E
A
G
G
S
S
G
D
R
R
R
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
S148
H
S
E
A
G
S
G
S
G
D
R
R
R
V
G
Rat
Rattus norvegicus
Q62829
544
60692
S142
Q
K
Y
M
S
F
T
S
G
D
K
S
A
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
E258
S
L
Q
Y
G
E
S
E
W
G
P
S
M
D
D
Chicken
Gallus gallus
XP_001233796
504
55780
E108
P
Q
R
P
R
G
Q
E
P
G
P
K
A
G
G
Frog
Xenopus laevis
NP_001082100
650
73749
S192
G
P
R
S
H
E
K
S
D
G
R
R
E
Y
P
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
H206
E
P
R
D
Y
S
D
H
V
V
R
R
E
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
L193
P
P
G
A
H
P
S
L
L
Y
N
S
Q
H
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
R162
H
N
Y
L
D
K
L
R
Q
N
A
S
N
V
T
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
D142
Q
Y
D
M
M
F
I
D
D
A
P
S
R
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
P264
K
S
F
P
S
K
N
P
L
K
N
S
S
P
P
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
N481
P
L
P
A
K
D
I
N
L
I
P
S
R
P
A
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
20
93.3
80
N.A.
86.6
26.6
N.A.
6.6
13.3
20
13.3
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
33.3
93.3
80
N.A.
86.6
33.3
N.A.
13.3
20
26.6
13.3
N.A.
13.3
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
40
0
0
0
0
0
7
14
0
14
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
7
7
7
7
14
34
0
0
0
7
7
% D
% Glu:
7
0
27
0
0
14
0
14
0
0
0
0
14
0
0
% E
% Phe:
0
0
14
0
7
14
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
0
34
27
20
0
34
20
0
7
0
14
47
% G
% His:
27
0
0
0
14
0
0
7
0
0
0
0
0
14
0
% H
% Ile:
0
0
0
0
0
0
14
0
0
7
0
0
0
0
0
% I
% Lys:
7
7
0
0
7
14
7
0
0
7
7
7
0
0
0
% K
% Leu:
0
14
0
7
0
0
7
7
20
0
0
0
0
0
0
% L
% Met:
0
0
0
14
7
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
0
0
0
7
7
0
7
14
0
7
0
0
% N
% Pro:
20
20
7
14
0
7
7
7
7
0
27
0
0
14
20
% P
% Gln:
14
7
7
7
0
0
7
0
7
0
0
0
7
0
0
% Q
% Arg:
7
0
20
0
7
0
0
7
7
0
40
40
40
0
0
% R
% Ser:
7
40
0
7
14
14
20
47
0
0
0
47
7
7
0
% S
% Thr:
0
0
0
0
0
7
7
0
0
7
0
0
7
7
7
% T
% Val:
0
0
0
0
0
0
0
0
7
7
0
0
0
27
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
7
7
14
7
7
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _