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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK4 All Species: 11.52
Human Site: S167 Identified Species: 18.1
UniProt: O96013 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O96013 NP_001014831.1 591 64072 S167 P K S S R E G S G G P Q E S S
Chimpanzee Pan troglodytes XP_525261 777 87548 E314 S L A Y S E S E W G P S L D D
Rhesus Macaque Macaca mulatta XP_001085295 565 60953 S167 P K S S R E G S G G P Q E P S
Dog Lupus familis XP_541627 592 64165 S167 P K S S R E G S G G P Q E S S
Cat Felis silvestris
Mouse Mus musculus Q8BTW9 593 64604 P167 P K S S R D G P G G P Q E A S
Rat Rattus norvegicus Q62829 544 60692 A161 H Q S N T K T A S E P P L A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 K277 P K S S Y V N K T S P Q P A M
Chicken Gallus gallus XP_001233796 504 55780 P127 P E Y P R P P P E R D G P A E
Frog Xenopus laevis NP_001082100 650 73749 R211 G H S D P V E R V V K R D K G
Zebra Danio Brachydanio rerio NP_001002222 663 74742 R225 P K S S Y T G R D S S P Q S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 R212 A T G P L A V R T D Q T N L Q
Honey Bee Apis mellifera XP_001122147 624 70155 P181 S N T Q N M I P N L Q N L N P
Nematode Worm Caenorhab. elegans Q17850 572 63863 S161 K P Q P Y S T S S L P Y H G N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 S283 E K S Y Y S S S S K K R K S G
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 V500 A I S T R P L V P P A S L P A
Conservation
Percent
Protein Identity: 100 49.2 91.7 95 N.A. 92.7 34 N.A. 54.2 65.6 64.7 65 N.A. 50 50 32.3 N.A.
Protein Similarity: 100 59.7 92.3 96.9 N.A. 94.4 52.4 N.A. 63.4 71.2 72.6 72 N.A. 61.5 62.5 47.5 N.A.
P-Site Identity: 100 20 93.3 100 N.A. 80 13.3 N.A. 40 13.3 6.6 40 N.A. 0 0 13.3 N.A.
P-Site Similarity: 100 26.6 93.3 100 N.A. 93.3 46.6 N.A. 46.6 26.6 20 46.6 N.A. 0 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.9 28.6
Protein Similarity: N.A. N.A. N.A. N.A. 41.2 41.4
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 0 0 7 0 7 0 0 7 0 0 27 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 7 0 0 7 7 7 0 7 7 7 % D
% Glu: 7 7 0 0 0 27 7 7 7 7 0 0 27 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 7 0 0 0 34 0 27 34 0 7 0 7 14 % G
% His: 7 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 7 47 0 0 0 7 0 7 0 7 14 0 7 7 0 % K
% Leu: 0 7 0 0 7 0 7 0 0 14 0 0 27 7 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 7 0 7 7 0 7 0 7 0 0 7 7 7 7 % N
% Pro: 47 7 0 20 7 14 7 20 7 7 54 14 14 14 20 % P
% Gln: 0 7 7 7 0 0 0 0 0 0 14 34 7 0 7 % Q
% Arg: 0 0 0 0 40 0 0 20 0 7 0 14 0 0 0 % R
% Ser: 14 0 67 40 7 14 14 34 20 14 7 14 0 27 27 % S
% Thr: 0 7 7 7 7 7 14 0 14 0 0 7 0 0 0 % T
% Val: 0 0 0 0 0 14 7 7 7 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 7 14 27 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _