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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
16.67
Human Site:
S244
Identified Species:
26.19
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
S244
L
A
I
P
Q
S
S
S
S
S
S
R
P
P
T
Chimpanzee
Pan troglodytes
XP_525261
777
87548
Q430
G
Y
S
S
S
S
H
Q
Y
P
S
G
Y
H
K
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
S244
L
A
V
P
Q
S
S
S
S
S
S
R
P
P
T
Dog
Lupus familis
XP_541627
592
64165
S245
A
V
P
Q
S
S
S
S
R
P
P
T
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
S243
G
L
A
A
P
Q
S
S
S
S
S
R
P
P
T
Rat
Rattus norvegicus
Q62829
544
60692
T237
S
S
T
L
Y
R
N
T
D
R
Q
R
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
Y375
Y
S
T
S
G
Y
Q
Y
P
S
G
Y
H
K
A
Chicken
Gallus gallus
XP_001233796
504
55780
R203
A
V
G
P
Q
Q
P
R
S
P
Q
R
E
P
Q
Frog
Xenopus laevis
NP_001082100
650
73749
S303
L
D
S
K
S
S
V
S
K
G
S
S
R
P
Q
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
S309
P
V
R
G
G
S
S
S
S
S
G
G
G
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q291
K
Q
G
G
D
Q
N
Q
N
P
L
H
P
H
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
L275
Q
N
T
L
L
H
K
L
Q
P
K
I
S
P
V
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
R237
A
I
P
D
R
P
A
R
T
L
S
I
Y
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S428
V
S
T
P
P
A
N
S
F
N
K
F
P
P
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
L581
A
A
Y
Q
Q
Q
L
L
Q
H
Q
Q
E
Q
A
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
13.3
93.3
20
N.A.
60
6.6
N.A.
6.6
33.3
33.3
40
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
13.3
100
20
N.A.
60
33.3
N.A.
13.3
33.3
33.3
40
N.A.
20
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
20
7
7
0
7
7
0
0
0
0
0
0
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
7
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% F
% Gly:
14
0
14
14
14
0
0
0
0
7
14
14
7
0
0
% G
% His:
0
0
0
0
0
7
7
0
0
7
0
7
7
14
0
% H
% Ile:
0
7
7
0
0
0
0
0
0
0
0
14
0
0
0
% I
% Lys:
7
0
0
7
0
0
7
0
7
0
14
0
7
14
14
% K
% Leu:
20
7
0
14
7
0
7
14
0
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
20
0
7
7
0
0
0
0
0
% N
% Pro:
7
0
14
27
14
7
7
0
7
34
7
0
34
47
0
% P
% Gln:
7
7
0
14
27
27
7
14
14
0
20
7
0
14
14
% Q
% Arg:
0
0
7
0
7
7
0
14
7
7
0
34
14
0
7
% R
% Ser:
7
20
14
14
20
40
34
47
34
34
40
7
7
0
14
% S
% Thr:
0
0
27
0
0
0
0
7
7
0
0
7
0
7
27
% T
% Val:
7
20
7
0
0
0
7
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
0
7
7
0
7
7
0
0
7
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _