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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
33.03
Human Site:
S46
Identified Species:
51.9
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
S46
W
Q
S
L
I
E
E
S
A
R
R
P
K
P
L
Chimpanzee
Pan troglodytes
XP_525261
777
87548
T104
W
H
S
L
L
A
D
T
A
N
R
P
K
P
M
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
S46
W
Q
S
L
I
E
E
S
A
R
R
P
K
P
L
Dog
Lupus familis
XP_541627
592
64165
S46
W
Q
S
L
I
E
E
S
A
R
R
P
K
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
S46
W
Q
S
L
I
E
E
S
A
R
R
P
K
P
L
Rat
Rattus norvegicus
Q62829
544
60692
N43
P
M
A
P
E
E
K
N
K
K
A
R
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
T46
W
H
S
L
L
A
D
T
A
N
R
P
K
P
M
Chicken
Gallus gallus
XP_001233796
504
55780
P10
P
F
G
E
V
F
V
P
S
P
G
G
A
T
E
Frog
Xenopus laevis
NP_001082100
650
73749
S46
W
Q
S
L
I
E
E
S
A
K
R
P
K
P
L
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
T47
W
Q
S
L
I
E
D
T
A
K
R
P
K
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
N46
W
A
S
I
V
G
N
N
Q
I
L
K
S
S
N
Honey Bee
Apis mellifera
XP_001122147
624
70155
N46
W
A
S
I
V
G
N
N
Q
I
L
K
S
T
N
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
K42
P
K
E
P
E
A
T
K
K
K
K
T
M
P
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S109
V
I
S
G
M
S
S
S
M
S
P
H
S
N
I
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S369
W
Q
R
L
I
S
E
S
G
I
T
E
K
D
R
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
6.6
N.A.
53.3
0
93.3
73.3
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
33.3
N.A.
80
13.3
100
93.3
N.A.
33.3
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
0
0
20
0
0
54
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
7
7
14
47
40
0
0
0
0
7
0
0
7
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
7
7
0
14
0
0
7
0
7
7
0
0
0
% G
% His:
0
14
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
14
47
0
0
0
0
20
0
0
0
0
7
% I
% Lys:
0
7
0
0
0
0
7
7
14
27
7
14
60
0
0
% K
% Leu:
0
0
0
60
14
0
0
0
0
0
14
0
7
0
34
% L
% Met:
0
7
0
0
7
0
0
0
7
0
0
0
7
0
14
% M
% Asn:
0
0
0
0
0
0
14
20
0
14
0
0
0
7
20
% N
% Pro:
20
0
0
14
0
0
0
7
0
7
7
54
0
60
0
% P
% Gln:
0
47
0
0
0
0
0
0
14
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
27
54
7
0
7
7
% R
% Ser:
0
0
74
0
0
14
7
47
7
7
0
0
20
7
7
% S
% Thr:
0
0
0
0
0
0
7
20
0
0
7
7
0
14
0
% T
% Val:
7
0
0
0
20
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
74
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _