KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
16.36
Human Site:
S74
Identified Species:
25.71
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
S74
P
K
T
I
V
R
G
S
K
G
A
K
D
G
A
Chimpanzee
Pan troglodytes
XP_525261
777
87548
N132
M
K
T
I
V
R
G
N
K
P
C
K
E
T
S
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
S74
P
K
T
I
V
R
G
S
K
G
A
K
D
G
A
Dog
Lupus familis
XP_541627
592
64165
S74
P
K
T
I
V
R
G
S
K
G
A
K
D
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
S74
P
K
T
I
V
R
G
S
K
G
A
K
D
G
A
Rat
Rattus norvegicus
Q62829
544
60692
S71
E
K
E
R
P
E
I
S
L
P
S
D
F
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
N74
M
K
T
I
V
R
G
N
K
P
R
K
E
T
S
Chicken
Gallus gallus
XP_001233796
504
55780
E38
S
L
T
W
L
L
D
E
F
E
N
M
S
V
S
Frog
Xenopus laevis
NP_001082100
650
73749
N74
Q
K
T
I
V
R
G
N
K
M
S
L
D
G
S
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
I75
T
I
V
R
G
R
K
I
G
D
D
G
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
T74
T
E
I
L
D
L
K
T
I
V
R
P
H
H
N
Honey Bee
Apis mellifera
XP_001122147
624
70155
T74
T
E
I
L
D
L
K
T
I
V
R
G
H
N
D
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P70
E
K
P
V
I
S
R
P
S
N
F
E
H
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
D137
N
T
S
N
I
T
P
D
H
S
A
D
N
T
F
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
P397
Y
K
E
T
T
E
K
P
Q
E
D
Q
Q
L
E
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
13.3
N.A.
53.3
6.6
60
6.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
20
N.A.
73.3
20
80
6.6
N.A.
20
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
14
0
7
7
0
7
14
14
34
0
7
% D
% Glu:
14
14
14
0
0
14
0
7
0
14
0
7
14
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
7
0
7
0
7
% F
% Gly:
0
0
0
0
7
0
47
0
7
27
0
14
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
20
7
7
% H
% Ile:
0
7
14
47
14
0
7
7
14
0
0
0
0
0
7
% I
% Lys:
0
67
0
0
0
0
27
0
47
0
0
40
0
0
0
% K
% Leu:
0
7
0
14
7
20
0
0
7
0
0
7
0
14
0
% L
% Met:
14
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
20
0
7
7
0
7
7
7
% N
% Pro:
27
0
7
0
7
0
7
14
0
20
0
7
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% Q
% Arg:
0
0
0
14
0
54
7
0
0
0
20
0
0
0
0
% R
% Ser:
7
0
7
0
0
7
0
34
7
7
14
0
14
0
27
% S
% Thr:
20
7
54
7
7
7
0
14
0
0
0
0
0
27
7
% T
% Val:
0
0
7
7
47
0
0
0
0
14
0
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _