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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
29.39
Human Site:
S97
Identified Species:
46.19
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
S97
E
N
M
S
V
T
R
S
N
S
L
R
R
D
S
Chimpanzee
Pan troglodytes
XP_525261
777
87548
S155
D
N
I
S
V
T
R
S
N
S
L
R
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
S97
E
N
M
S
V
T
R
S
N
S
L
R
R
D
S
Dog
Lupus familis
XP_541627
592
64165
S97
E
N
M
S
V
T
R
S
N
S
L
R
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
S97
E
N
M
S
V
T
R
S
N
S
L
R
R
E
S
Rat
Rattus norvegicus
Q62829
544
60692
I94
V
T
G
E
F
T
G
I
P
E
Q
W
A
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
S97
D
N
I
S
V
T
R
S
N
S
L
R
K
E
S
Chicken
Gallus gallus
XP_001233796
504
55780
R61
S
P
P
F
P
P
R
R
D
Q
L
C
Q
E
N
Frog
Xenopus laevis
NP_001082100
650
73749
S97
D
D
M
S
V
C
R
S
N
S
L
R
R
E
S
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
S98
M
S
V
I
R
S
N
S
L
R
R
G
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
M97
L
N
S
S
S
T
M
M
M
G
S
M
A
P
M
Honey Bee
Apis mellifera
XP_001122147
624
70155
L97
E
K
N
T
E
N
G
L
P
K
T
S
T
V
A
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
E93
G
E
F
T
G
M
P
E
A
W
A
R
L
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
L160
D
H
Q
F
N
D
T
L
L
S
K
L
S
L
T
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
T420
D
F
R
S
P
P
V
T
G
T
A
P
L
V
L
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
93.3
6.6
N.A.
73.3
13.3
73.3
6.6
N.A.
20
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
40
93.3
26.6
N.A.
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
14
0
14
0
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% C
% Asp:
34
7
0
0
0
7
0
0
7
0
0
0
0
20
0
% D
% Glu:
34
7
0
7
7
0
0
7
0
7
0
0
0
34
0
% E
% Phe:
0
7
7
14
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
0
7
0
14
0
7
7
0
7
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
7
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
7
7
0
14
0
0
% K
% Leu:
7
0
0
0
0
0
0
14
14
0
54
7
14
14
14
% L
% Met:
7
0
34
0
0
7
7
7
7
0
0
7
0
0
7
% M
% Asn:
0
47
7
0
7
7
7
0
47
0
0
0
0
0
7
% N
% Pro:
0
7
7
0
14
14
7
0
14
0
0
7
0
14
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
7
7
0
7
0
0
% Q
% Arg:
0
0
7
0
7
0
54
7
0
7
7
54
34
7
0
% R
% Ser:
7
7
7
60
7
7
0
54
0
54
7
7
14
0
47
% S
% Thr:
0
7
0
14
0
54
7
7
0
7
7
0
7
0
14
% T
% Val:
7
0
7
0
47
0
7
0
0
0
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _