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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
16.36
Human Site:
T207
Identified Species:
25.71
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
T207
A
A
G
R
P
F
N
T
Y
P
R
A
D
T
D
Chimpanzee
Pan troglodytes
XP_525261
777
87548
M354
G
S
G
L
Q
E
P
M
M
P
F
G
A
S
A
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
T207
A
A
G
R
P
F
N
T
Y
P
R
A
D
T
D
Dog
Lupus familis
XP_541627
592
64165
T207
A
A
G
R
P
F
N
T
Y
P
R
A
D
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
T207
A
A
G
R
P
F
N
T
Y
P
R
A
D
T
D
Rat
Rattus norvegicus
Q62829
544
60692
I201
R
P
E
H
T
K
S
I
Y
T
R
S
V
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
S317
Q
Q
G
H
S
Y
S
S
Y
T
Y
P
R
L
S
Chicken
Gallus gallus
XP_001233796
504
55780
K167
P
P
G
P
P
R
S
K
V
P
E
P
P
T
G
Frog
Xenopus laevis
NP_001082100
650
73749
P251
S
G
P
N
I
R
T
P
G
S
S
S
T
D
G
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
F265
A
Q
Q
T
G
R
P
F
N
T
Y
P
R
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
N252
V
A
S
G
T
R
S
N
H
S
H
T
N
N
G
Honey Bee
Apis mellifera
XP_001122147
624
70155
C221
S
P
I
N
T
P
Q
C
S
I
Q
S
P
S
T
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
V201
V
P
P
T
T
F
S
V
N
E
N
R
S
S
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S323
D
K
R
A
S
S
S
S
N
N
S
S
S
S
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
H540
Q
H
M
Y
Q
E
E
H
R
N
R
S
R
S
N
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
13.3
26.6
0
6.6
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
33.3
N.A.
33.3
33.3
13.3
20
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
34
0
7
0
0
0
0
0
0
0
27
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
27
7
27
% D
% Glu:
0
0
7
0
0
14
7
0
0
7
7
0
0
0
14
% E
% Phe:
0
0
0
0
0
34
0
7
0
0
7
0
0
0
0
% F
% Gly:
7
7
47
7
7
0
0
0
7
0
0
7
0
0
20
% G
% His:
0
7
0
14
0
0
0
7
7
0
7
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
7
0
0
0
0
7
7
0
0
0
0
0
7
% M
% Asn:
0
0
0
14
0
0
27
7
20
14
7
0
7
7
7
% N
% Pro:
7
27
14
7
34
7
14
7
0
40
0
20
14
0
0
% P
% Gln:
14
14
7
0
14
0
7
0
0
0
7
0
0
0
0
% Q
% Arg:
7
0
7
27
0
27
0
0
7
0
40
7
20
0
0
% R
% Ser:
14
7
7
0
14
7
40
14
7
14
14
34
14
40
14
% S
% Thr:
0
0
0
14
27
0
7
27
0
20
0
7
7
34
7
% T
% Val:
14
0
0
0
0
0
0
7
7
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
7
0
0
40
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _