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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK4
All Species:
39.39
Human Site:
T23
Identified Species:
61.9
UniProt:
O96013
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96013
NP_001014831.1
591
64072
T23
N
F
E
H
R
V
H
T
G
F
D
Q
H
E
Q
Chimpanzee
Pan troglodytes
XP_525261
777
87548
T81
N
F
E
H
R
V
H
T
G
F
D
P
Q
E
Q
Rhesus Macaque
Macaca mulatta
XP_001085295
565
60953
T23
N
F
E
H
R
V
H
T
G
F
D
Q
H
E
Q
Dog
Lupus familis
XP_541627
592
64165
T23
N
F
E
H
R
V
H
T
G
F
D
Q
H
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW9
593
64604
T23
N
F
E
H
R
V
H
T
G
F
D
Q
H
E
Q
Rat
Rattus norvegicus
Q62829
544
60692
S20
A
P
P
L
R
M
N
S
N
N
R
D
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
T23
N
F
E
H
R
V
H
T
G
F
D
P
R
E
Q
Chicken
Gallus gallus
XP_001233796
504
55780
Frog
Xenopus laevis
NP_001082100
650
73749
T23
N
F
E
H
R
V
H
T
G
F
D
Q
Q
E
Q
Zebra Danio
Brachydanio rerio
NP_001002222
663
74742
T24
N
F
E
H
R
V
H
T
D
F
D
E
Q
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
T23
N
F
E
H
R
V
H
T
G
F
D
K
R
E
N
Honey Bee
Apis mellifera
XP_001122147
624
70155
T23
N
F
E
H
R
V
H
T
G
F
D
K
R
E
G
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
S19
P
A
P
P
I
R
F
S
S
S
A
T
R
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
V86
N
D
D
D
N
N
V
V
S
L
D
D
P
I
Q
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
V346
N
P
V
H
V
T
H
V
G
Y
D
S
N
T
G
Conservation
Percent
Protein Identity:
100
49.2
91.7
95
N.A.
92.7
34
N.A.
54.2
65.6
64.7
65
N.A.
50
50
32.3
N.A.
Protein Similarity:
100
59.7
92.3
96.9
N.A.
94.4
52.4
N.A.
63.4
71.2
72.6
72
N.A.
61.5
62.5
47.5
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
100
6.6
N.A.
86.6
0
93.3
80
N.A.
80
80
6.6
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
26.6
N.A.
86.6
0
93.3
86.6
N.A.
86.6
86.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.9
28.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
41.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
0
0
0
0
7
0
80
14
0
0
0
% D
% Glu:
0
0
67
0
0
0
0
0
0
0
0
7
0
74
0
% E
% Phe:
0
67
0
0
0
0
7
0
0
67
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
14
% G
% His:
0
0
0
74
0
0
74
0
0
0
0
0
27
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
80
0
0
0
7
7
7
0
7
7
0
0
7
0
14
% N
% Pro:
7
14
14
7
0
0
0
0
0
0
0
14
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
34
20
0
60
% Q
% Arg:
0
0
0
0
74
7
0
0
0
0
7
0
27
0
0
% R
% Ser:
0
0
0
0
0
0
0
14
14
7
0
7
7
7
0
% S
% Thr:
0
0
0
0
0
7
0
67
0
0
0
7
0
7
0
% T
% Val:
0
0
7
0
7
67
7
14
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _