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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6A
All Species:
32.73
Human Site:
S123
Identified Species:
60
UniProt:
O96019
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96019
NP_004292.1
429
47461
S123
S
L
H
P
V
L
M
S
E
A
P
W
N
T
R
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
L81
T
R
A
K
R
E
K
L
T
E
L
M
F
E
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848224
453
50289
S147
S
L
H
P
V
L
M
S
E
A
P
W
N
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2N8
429
47429
S123
S
L
H
P
V
L
M
S
E
A
P
W
N
T
R
Rat
Rattus norvegicus
NP_001034122
429
47402
S123
S
L
H
P
V
L
M
S
E
A
P
W
N
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
L10
T
R
A
K
R
E
K
L
T
E
L
M
F
E
H
Chicken
Gallus gallus
XP_422784
720
79965
S123
S
L
H
P
V
L
M
S
E
A
P
W
N
T
R
Frog
Xenopus laevis
NP_001080451
429
47605
S123
N
L
H
P
V
L
M
S
E
A
A
W
N
T
R
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
S123
G
L
H
P
V
L
M
S
E
A
S
W
N
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
S128
E
Y
H
P
V
L
F
S
E
A
S
W
N
V
R
Honey Bee
Apis mellifera
XP_625202
440
49061
S131
E
Y
H
P
V
L
F
S
E
S
P
W
N
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P53472
376
41830
D81
H
G
I
V
T
N
W
D
D
M
E
K
I
W
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
A130
T
E
H
P
M
L
L
A
E
P
P
L
N
T
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
N.A.
92.9
N.A.
98.8
98.5
N.A.
70.1
59
92.3
88.3
N.A.
55.9
60.6
N.A.
34.9
Protein Similarity:
100
83.4
N.A.
93.5
N.A.
100
100
N.A.
70.6
59.5
96.5
94.8
N.A.
73.4
77
N.A.
55.7
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
0
100
86.6
86.6
N.A.
66.6
66.6
N.A.
0
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
6.6
100
93.3
86.6
N.A.
66.6
73.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
8
0
62
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
16
8
0
0
0
16
0
0
77
16
8
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
16
0
0
0
0
0
16
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
77
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
16
0
0
16
0
0
0
0
8
0
0
0
% K
% Leu:
0
54
0
0
0
77
8
16
0
0
16
8
0
0
0
% L
% Met:
0
0
0
0
8
0
54
0
0
8
0
16
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
77
0
0
% N
% Pro:
0
0
0
77
0
0
0
0
0
8
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
16
0
0
16
0
0
0
0
0
0
0
0
0
70
% R
% Ser:
39
0
0
0
0
0
0
70
0
8
16
0
0
0
0
% S
% Thr:
24
0
0
0
8
0
0
0
16
0
0
0
0
62
0
% T
% Val:
0
0
0
8
70
0
0
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
70
0
8
0
% W
% Tyr:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _