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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6A
All Species:
22.73
Human Site:
S233
Identified Species:
41.67
UniProt:
O96019
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96019
NP_004292.1
429
47461
S233
K
E
A
V
R
E
G
S
P
A
N
W
K
R
K
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
L188
N
W
K
K
K
E
K
L
P
Q
V
S
K
S
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848224
453
50289
S257
K
E
A
V
R
E
G
S
P
A
N
W
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2N8
429
47429
S233
K
E
A
V
R
E
G
S
P
A
N
W
K
R
K
Rat
Rattus norvegicus
NP_001034122
429
47402
S233
K
E
A
V
R
E
G
S
P
A
N
W
K
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
L117
N
W
K
R
K
E
K
L
P
Q
V
T
R
S
W
Chicken
Gallus gallus
XP_422784
720
79965
S233
K
E
A
V
R
E
G
S
P
A
N
W
K
R
K
Frog
Xenopus laevis
NP_001080451
429
47605
A233
K
E
A
V
R
E
G
A
P
P
N
W
K
R
K
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
T233
K
D
S
V
R
E
G
T
P
A
S
W
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
D238
K
D
V
V
K
E
R
D
N
G
R
F
T
L
R
Honey Bee
Apis mellifera
XP_625202
440
49061
E241
K
E
V
V
K
D
H
E
K
P
R
W
I
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P53472
376
41830
D188
L
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
A237
F
K
R
K
E
V
R
A
G
E
F
Q
V
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
N.A.
92.9
N.A.
98.8
98.5
N.A.
70.1
59
92.3
88.3
N.A.
55.9
60.6
N.A.
34.9
Protein Similarity:
100
83.4
N.A.
93.5
N.A.
100
100
N.A.
70.6
59.5
96.5
94.8
N.A.
73.4
77
N.A.
55.7
P-Site Identity:
100
20
N.A.
100
N.A.
100
100
N.A.
13.3
100
86.6
66.6
N.A.
20
33.3
N.A.
0
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
26.6
100
93.3
100
N.A.
46.6
53.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
0
0
0
0
16
0
47
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
8
8
0
16
0
0
0
0
0
0
8
% D
% Glu:
0
54
0
0
8
77
0
8
0
8
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
54
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% I
% Lys:
70
8
16
16
31
0
16
0
8
0
0
8
62
16
62
% K
% Leu:
8
0
0
0
0
8
0
16
0
8
0
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
8
0
47
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
70
16
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
0
8
0
0
0
% Q
% Arg:
0
0
8
16
54
0
16
0
0
0
16
0
8
47
8
% R
% Ser:
0
0
8
0
0
0
0
39
0
0
8
8
0
16
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
8
8
0
8
% T
% Val:
0
0
16
70
0
8
0
0
0
0
16
0
8
0
0
% V
% Trp:
0
16
0
0
0
0
0
0
0
0
0
62
0
0
16
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _