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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6A
All Species:
26.97
Human Site:
S318
Identified Species:
49.44
UniProt:
O96019
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96019
NP_004292.1
429
47461
S318
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
G269
L
S
G
N
T
M
L
G
V
G
H
V
V
T
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848224
453
50289
S342
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2N8
429
47429
S318
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Rat
Rattus norvegicus
NP_001034122
429
47402
S318
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
G198
L
S
G
N
T
M
L
G
V
S
H
V
V
T
T
Chicken
Gallus gallus
XP_422784
720
79965
S609
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Frog
Xenopus laevis
NP_001080451
429
47605
S318
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
S318
P
S
N
A
K
G
L
S
G
N
T
M
L
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
G320
L
F
D
N
A
M
L
G
A
G
Q
L
A
S
T
Honey Bee
Apis mellifera
XP_625202
440
49061
V329
V
Q
M
R
G
G
M
V
G
N
T
M
L
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P53472
376
41830
E271
Q
P
A
F
L
G
M
E
S
A
G
I
H
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
M330
G
M
E
K
Y
A
E
M
I
P
S
V
R
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
N.A.
92.9
N.A.
98.8
98.5
N.A.
70.1
59
92.3
88.3
N.A.
55.9
60.6
N.A.
34.9
Protein Similarity:
100
83.4
N.A.
93.5
N.A.
100
100
N.A.
70.6
59.5
96.5
94.8
N.A.
73.4
77
N.A.
55.7
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
13.3
100
100
93.3
N.A.
6.6
53.3
N.A.
6.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
33.3
100
100
93.3
N.A.
20
60
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
0
0
8
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
8
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
0
8
70
0
24
62
16
8
0
0
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
54
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
24
0
0
0
8
0
77
0
0
0
0
8
62
0
8
% L
% Met:
0
8
8
0
0
24
16
8
0
0
0
62
0
0
0
% M
% Asn:
0
0
54
24
0
0
0
0
0
62
0
0
0
0
0
% N
% Pro:
54
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
70
0
0
0
0
0
54
8
8
8
0
0
8
0
% S
% Thr:
0
0
0
0
16
0
0
0
0
0
62
0
0
16
31
% T
% Val:
8
0
0
47
0
0
0
8
16
0
0
24
16
0
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _