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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6A
All Species:
34.24
Human Site:
T72
Identified Species:
62.78
UniProt:
O96019
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O96019
NP_004292.1
429
47461
T72
G
P
T
Y
Y
I
D
T
N
A
L
R
V
P
R
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
E30
V
R
A
G
Y
A
G
E
D
C
P
K
N
G
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848224
453
50289
T96
G
P
T
Y
Y
I
D
T
N
A
L
R
V
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2N8
429
47429
T72
G
P
T
Y
Y
I
D
T
N
A
L
R
V
P
R
Rat
Rattus norvegicus
NP_001034122
429
47402
T72
G
P
T
Y
Y
I
D
T
N
A
L
R
V
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
Chicken
Gallus gallus
XP_422784
720
79965
T72
G
P
T
Y
Y
I
D
T
N
A
L
R
V
P
R
Frog
Xenopus laevis
NP_001080451
429
47605
T72
S
P
T
Y
Y
I
D
T
N
S
L
R
V
P
R
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
T72
G
T
T
Y
F
I
D
T
N
Q
L
R
V
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
T77
Q
R
K
F
Y
V
D
T
N
Y
V
T
V
P
R
Honey Bee
Apis mellifera
XP_625202
440
49061
T80
G
I
K
Y
Y
I
D
T
T
I
L
H
V
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P53472
376
41830
A30
A
G
D
D
A
P
R
A
V
F
P
S
I
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
S79
K
R
K
L
Y
V
G
S
Q
A
M
S
Y
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
N.A.
92.9
N.A.
98.8
98.5
N.A.
70.1
59
92.3
88.3
N.A.
55.9
60.6
N.A.
34.9
Protein Similarity:
100
83.4
N.A.
93.5
N.A.
100
100
N.A.
70.6
59.5
96.5
94.8
N.A.
73.4
77
N.A.
55.7
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
0
100
86.6
80
N.A.
46.6
66.6
N.A.
0
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
0
100
93.3
86.6
N.A.
66.6
66.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
8
0
47
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
70
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
54
8
0
8
0
0
16
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
62
0
0
0
8
0
0
8
0
0
% I
% Lys:
8
0
24
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
62
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
62
0
0
0
8
0
0
% N
% Pro:
0
47
0
0
0
8
0
0
0
0
16
0
0
70
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
24
0
0
0
0
8
0
0
0
0
54
0
8
77
% R
% Ser:
8
0
0
0
0
0
0
8
0
8
0
16
0
0
0
% S
% Thr:
0
8
54
0
0
0
0
70
8
0
0
8
0
0
0
% T
% Val:
8
0
0
0
0
16
0
0
8
0
8
0
70
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
62
77
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _