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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH1B
All Species:
28.18
Human Site:
Y150
Identified Species:
77.5
UniProt:
P00325
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00325
NP_000659.2
375
39855
Y150
G
T
S
T
F
S
Q
Y
T
V
V
D
E
N
A
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
Y150
G
T
S
T
F
S
Q
Y
T
V
V
D
E
N
A
Rhesus Macaque
Macaca mulatta
P28469
375
39894
Y150
G
V
S
T
F
S
Q
Y
T
V
V
D
E
N
A
Dog
Lupus familis
XP_535667
375
39781
Y150
G
I
S
T
F
S
Q
Y
T
V
V
D
E
F
S
Cat
Felis silvestris
Mouse
Mus musculus
P00329
375
39753
Y150
S
T
S
T
F
S
Q
Y
T
V
V
D
D
I
A
Rat
Rattus norvegicus
P06757
376
39627
Y151
S
T
S
T
F
S
Q
Y
T
V
V
D
D
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518178
335
35465
L132
A
P
L
E
K
V
C
L
I
G
C
G
F
S
T
Chicken
Gallus gallus
P23991
376
39789
Y151
G
T
S
T
F
T
E
Y
T
V
V
H
E
T
A
Frog
Xenopus laevis
NP_001086118
378
40059
Y151
S
T
S
T
F
T
E
Y
T
V
L
D
E
I
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.4
85.8
N.A.
83.4
81.6
N.A.
69
73.4
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96
93.8
N.A.
92.5
90.6
N.A.
79.7
85.3
79.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
0
73.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
6.6
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
78
23
0
0
% D
% Glu:
0
0
0
12
0
0
23
0
0
0
0
0
67
0
0
% E
% Phe:
0
0
0
0
89
0
0
0
0
0
0
0
12
12
0
% F
% Gly:
56
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
12
0
0
0
0
34
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
12
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
0
89
0
0
67
0
0
0
0
0
0
0
12
12
% S
% Thr:
0
67
0
89
0
23
0
0
89
0
0
0
0
12
12
% T
% Val:
0
12
0
0
0
12
0
0
0
89
78
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _