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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADH1C All Species: 31.82
Human Site: S325 Identified Species: 87.5
UniProt: P00326 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00326 NP_000660.1 375 39868 S325 A I F G G F K S K E S V P K L
Chimpanzee Pan troglodytes Q5R1W2 375 39808 S325 A V Y G G F K S K E G I P K L
Rhesus Macaque Macaca mulatta P28469 375 39894 S325 A V Y G G F K S K E D I P K L
Dog Lupus familis XP_535667 375 39781 S325 A I F G G F K S K D S V P K L
Cat Felis silvestris
Mouse Mus musculus P00329 375 39753 S325 A I F G G F K S K D S V P K L
Rat Rattus norvegicus P06757 376 39627 S326 A I F G G F K S K D A V P K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518178 335 35465 S288 G G W K S R D S V P K L V S D
Chicken Gallus gallus P23991 376 39789 S326 S V F G G W K S K D A V P K L
Frog Xenopus laevis NP_001086118 378 40059 S326 A L F G G W K S R D D V P K L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 92 86.6 N.A. 85 82.1 N.A. 69 74.1 66.9 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 96.2 94.9 N.A. 93.3 90.9 N.A. 80.2 85.6 79.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 73.3 93.3 N.A. 93.3 86.6 N.A. 6.6 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 100 N.A. 20 100 93.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 78 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 56 23 0 0 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 34 0 0 0 0 0 % E
% Phe: 0 0 67 0 0 67 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 12 0 89 89 0 0 0 0 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 45 0 0 0 0 0 0 0 0 0 23 0 0 0 % I
% Lys: 0 0 0 12 0 0 89 0 78 0 12 0 0 89 0 % K
% Leu: 0 12 0 0 0 0 0 0 0 0 0 12 0 0 89 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 12 0 0 89 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % R
% Ser: 12 0 0 0 12 0 0 100 0 0 34 0 0 12 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 34 0 0 0 0 0 0 12 0 0 67 12 0 0 % V
% Trp: 0 0 12 0 0 23 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _