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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LDHA
All Species:
40.91
Human Site:
S196
Identified Species:
100
UniProt:
P00338
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00338
NP_005557.1
332
36689
S196
V
L
G
E
H
G
D
S
S
V
P
V
W
S
G
Chimpanzee
Pan troglodytes
Q5R1W9
332
36644
S196
V
L
G
E
H
G
D
S
S
V
P
V
W
S
G
Rhesus Macaque
Macaca mulatta
XP_001084264
332
36613
S196
V
L
G
E
H
G
D
S
S
V
P
V
W
S
G
Dog
Lupus familis
XP_534084
361
39780
S225
V
L
G
E
H
G
D
S
S
V
P
V
W
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P06151
332
36480
S196
V
L
G
E
H
G
D
S
S
V
P
V
W
S
G
Rat
Rattus norvegicus
P04642
332
36432
S196
V
L
G
E
H
G
D
S
S
V
P
V
W
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121092
332
36433
S196
V
I
G
E
H
G
D
S
S
V
P
V
W
S
G
Chicken
Gallus gallus
P00340
332
36496
S196
I
V
G
E
H
G
D
S
S
V
P
V
W
S
G
Frog
Xenopus laevis
NP_001080702
332
36454
S196
V
I
G
E
H
G
D
S
S
V
P
V
W
S
G
Zebra Danio
Brachydanio rerio
Q9PVK5
333
36228
S197
V
V
G
E
H
G
D
S
S
V
P
V
W
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
88
N.A.
93.9
94.2
N.A.
92.4
84.9
84.9
76.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
90.5
N.A.
97.5
97.5
N.A.
96.9
94.8
95.1
90
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
100
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
100
0
0
0
0
100
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
90
20
0
0
0
0
0
0
0
100
0
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _