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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLUD1 All Species: 31.82
Human Site: Y458 Identified Species: 58.33
UniProt: P00367 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00367 NP_005262.1 558 61398 Y458 Y G R L T F K Y E R D S N Y H
Chimpanzee Pan troglodytes Q64HZ8 558 61420 Y458 Y G R L T F K Y E R D S N Y H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540979 479 53188 I380 A P R V K A K I I A E G A N G
Cat Felis silvestris
Mouse Mus musculus P26443 558 61318 Y458 Y G R L T F K Y E R D S N Y H
Rat Rattus norvegicus P10860 558 61397 Y458 Y G R L T F K Y E R D S N Y H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P00368 503 55179 Y403 Y G R L T F K Y E R D S N Y H
Frog Xenopus laevis NP_001087023 540 59547 Y440 Y G R L T F K Y E R D S N Y H
Zebra Danio Brachydanio rerio NP_997741 544 60096 Y444 Y G R L T F K Y E R D S N Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54385 562 62518 Q463 Y H L L A S V Q Q S I E R I I
Honey Bee Apis mellifera XP_392776 553 61624 Y454 Y G R L T F K Y E K E S N Y H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789257 558 61370 E458 H L L Q S V Q E S L E R K F G
Poplar Tree Populus trichocarpa
Maize Zea mays Q43260 411 44004 N312 K Y I I E A A N H P T D P E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38946 411 44681 N312 K F I V E A A N H P T D P D A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 N.A. 77.9 N.A. 97.8 96.9 N.A. N.A. 82 87.4 84.4 N.A. 66 67.5 N.A. 71.5
Protein Similarity: 100 97.4 N.A. 80.2 N.A. 98.7 98 N.A. N.A. 85.6 93.3 92.1 N.A. 80.4 82 N.A. 83.8
P-Site Identity: 100 100 N.A. 13.3 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 13.3 86.6 N.A. 0
P-Site Similarity: 100 100 N.A. 26.6 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 20 100 N.A. 33.3
Percent
Protein Identity: N.A. 32.9 N.A. 34.4 N.A. N.A.
Protein Similarity: N.A. 47.3 N.A. 47.4 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 24 16 0 0 8 0 0 8 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 54 16 0 8 0 % D
% Glu: 0 0 0 0 16 0 0 8 62 0 24 8 0 8 0 % E
% Phe: 0 8 0 0 0 62 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 62 0 0 0 0 0 0 0 0 0 8 0 0 16 % G
% His: 8 8 0 0 0 0 0 0 16 0 0 0 0 0 62 % H
% Ile: 0 0 16 8 0 0 0 8 8 0 8 0 0 8 8 % I
% Lys: 16 0 0 0 8 0 70 0 0 8 0 0 8 0 0 % K
% Leu: 0 8 16 70 0 0 0 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 0 0 0 62 8 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 16 0 0 16 0 0 % P
% Gln: 0 0 0 8 0 0 8 8 8 0 0 0 0 0 0 % Q
% Arg: 0 0 70 0 0 0 0 0 0 54 0 8 8 0 0 % R
% Ser: 0 0 0 0 8 8 0 0 8 8 0 62 0 0 0 % S
% Thr: 0 0 0 0 62 0 0 0 0 0 16 0 0 0 0 % T
% Val: 0 0 0 16 0 8 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 70 8 0 0 0 0 0 62 0 0 0 0 0 62 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _