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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOD1 All Species: 43.64
Human Site: S135 Identified Species: 87.27
UniProt: P00441 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00441 NP_000445.1 154 15936 S135 G K G G N E E S T K T G N A G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q8HXQ0 154 15964 S135 G K G G N E E S K K T G N A G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P08228 154 15924 S135 G K G G N E E S T K T G N A G
Rat Rattus norvegicus P07632 154 15893 S135 G K G G N E E S T K T G N A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P80566 154 15685 S134 G R G G D N E S K L T G N A G
Frog Xenopus laevis P15107 151 15400 S132 G K G G N D E S L K T G N A G
Zebra Danio Brachydanio rerio O73872 154 15934 S135 G K G G N E E S L K T G N A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61851 153 15680 S133 G Q G G H E L S K S T G N A G
Honey Bee Apis mellifera NP_001171498 152 15615 S132 G K G G V E L S K T T G N A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002331456 210 21603 S190 G K G G H E L S S T T G N A G
Maize Zea mays P11428 151 15085 S132 G K G G H E L S K S T G N A G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O78310 216 22225 S196 G K G G H E L S L T T G N A G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 91.5 N.A. N.A. 83.7 83.1 N.A. N.A. 74 66.8 70.1 N.A. 61 66.8 N.A. N.A.
Protein Similarity: 100 N.A. 92.8 N.A. N.A. 88.9 88.9 N.A. N.A. 86.3 77.9 76.6 N.A. 73.3 75.3 N.A. N.A.
P-Site Identity: 100 N.A. 93.3 N.A. N.A. 100 100 N.A. N.A. 66.6 86.6 93.3 N.A. 66.6 73.3 N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 N.A. N.A. 100 100 N.A. N.A. 80 93.3 93.3 N.A. 80 73.3 N.A. N.A.
Percent
Protein Identity: 42.8 61 N.A. 40.7 N.A. N.A.
Protein Similarity: 52.8 71.4 N.A. 51.8 N.A. N.A.
P-Site Identity: 73.3 73.3 N.A. 73.3 N.A. N.A.
P-Site Similarity: 86.6 80 N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 84 59 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 100 0 100 100 0 0 0 0 0 0 0 100 0 0 100 % G
% His: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 84 0 0 0 0 0 0 42 50 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 42 0 25 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 50 9 0 0 0 0 0 0 100 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 9 17 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 25 25 100 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _