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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOD1 All Species: 12.42
Human Site: S69 Identified Species: 24.85
UniProt: P00441 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00441 NP_000445.1 154 15936 S69 G P H F N P L S R K H G G P K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q8HXQ0 154 15964 S69 G P H F N P L S R Q H G G P K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P08228 154 15924 S69 G P H F N P H S K K H G G P A
Rat Rattus norvegicus P07632 154 15893 S69 G P H F N P H S K K H G G P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P80566 154 15685 G69 G A H F N P E G K Q H G G P K
Frog Xenopus laevis P15107 151 15400 N67 G S H F N P E N K N H G A P G
Zebra Danio Brachydanio rerio O73872 154 15934 D69 G P H F N P H D K T H G G P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61851 153 15680 G67 G P H F N P Y G K E H G A P V
Honey Bee Apis mellifera NP_001171498 152 15615 G66 G A H F N P L G K D H G G P D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002331456 210 21603 K124 G P H F N P K K L T H G A P E
Maize Zea mays P11428 151 15085 G66 G P H F N P V G K E H G A P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O78310 216 22225 N130 G P H F N P N N M T H G A P E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 91.5 N.A. N.A. 83.7 83.1 N.A. N.A. 74 66.8 70.1 N.A. 61 66.8 N.A. N.A.
Protein Similarity: 100 N.A. 92.8 N.A. N.A. 88.9 88.9 N.A. N.A. 86.3 77.9 76.6 N.A. 73.3 75.3 N.A. N.A.
P-Site Identity: 100 N.A. 93.3 N.A. N.A. 80 80 N.A. N.A. 66.6 53.3 66.6 N.A. 60 66.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 N.A. N.A. 86.6 86.6 N.A. N.A. 80 66.6 73.3 N.A. 73.3 73.3 N.A. N.A.
Percent
Protein Identity: 42.8 61 N.A. 40.7 N.A. N.A.
Protein Similarity: 52.8 71.4 N.A. 51.8 N.A. N.A.
P-Site Identity: 60 60 N.A. 60 N.A. N.A.
P-Site Similarity: 66.6 86.6 N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 0 0 0 0 0 0 0 42 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 17 0 0 17 0 0 0 0 25 % E
% Phe: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 100 0 0 0 0 0 0 34 0 0 0 100 59 0 9 % G
% His: 0 0 100 0 0 0 25 0 0 0 100 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 9 67 25 0 0 0 0 25 % K
% Leu: 0 0 0 0 0 0 25 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 100 0 9 17 0 9 0 0 0 0 0 % N
% Pro: 0 75 0 0 0 100 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 0 0 34 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _