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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CP All Species: 21.52
Human Site: S419 Identified Species: 59.17
UniProt: P00450 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00450 NP_000087.1 1065 122205 S419 G T T R I G G S Y K K L V Y R
Chimpanzee Pan troglodytes XP_508699 1298 146493 K566 G D N R I G G K Y W K V Q Y T
Rhesus Macaque Macaca mulatta XP_001109373 1069 122627 S419 G T T R I G G S Y K K L V Y R
Dog Lupus familis XP_534301 1065 122544 S419 G T T R I G G S Y K K L V Y R
Cat Felis silvestris
Mouse Mus musculus Q61147 1061 121133 S418 G A T R I G G S Y K K M A Y R
Rat Rattus norvegicus P13635 1059 120822 S418 G A T R I G G S Y K K L V Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508540 962 108933 G367 R F T K S N E G S F Y K Q F S
Chicken Gallus gallus XP_001235149 1079 123193 S419 S E T R I G G S Y K K A I Y K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571877 1087 124540 Y421 N D R I G G K Y K K V Q Y V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.7 96.6 84.3 N.A. 83.2 82.1 N.A. 66.1 59.8 N.A. 54.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57.4 97.7 91.6 N.A. 90.8 89.3 N.A. 75.9 75.4 N.A. 71.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 100 N.A. 80 93.3 N.A. 6.6 66.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 100 100 N.A. 86.6 93.3 N.A. 20 80 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 0 0 0 0 0 0 0 0 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 12 % E
% Phe: 0 12 0 0 0 0 0 0 0 12 0 0 0 12 0 % F
% Gly: 67 0 0 0 12 89 78 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 78 0 0 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 12 0 0 12 12 12 78 78 12 0 0 12 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 12 0 12 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 12 23 0 0 % Q
% Arg: 12 0 12 78 0 0 0 0 0 0 0 0 0 0 56 % R
% Ser: 12 0 0 0 12 0 0 67 12 0 0 0 0 0 12 % S
% Thr: 0 34 78 0 0 0 0 0 0 0 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 12 12 45 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 78 0 12 0 12 78 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _