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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CP
All Species:
7.58
Human Site:
Y490
Identified Species:
20.83
UniProt:
P00450
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00450
NP_000087.1
1065
122205
Y490
N
K
N
N
E
G
T
Y
Y
S
P
N
Y
N
P
Chimpanzee
Pan troglodytes
XP_508699
1298
146493
D630
L
P
H
G
V
I
Y
D
K
A
S
D
A
A
P
Rhesus Macaque
Macaca mulatta
XP_001109373
1069
122627
Y490
N
K
N
N
E
G
T
Y
Y
S
S
H
Y
N
P
Dog
Lupus familis
XP_534301
1065
122544
Y490
S
K
N
Y
E
G
T
Y
Y
S
S
H
N
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61147
1061
121133
N485
G
V
S
F
T
A
E
N
E
G
T
Y
Y
G
P
Rat
Rattus norvegicus
P13635
1059
120822
E484
M
G
V
R
F
T
K
E
N
E
G
T
Y
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508540
962
108933
I427
G
V
D
P
V
S
E
I
S
S
G
L
I
G
P
Chicken
Gallus gallus
XP_001235149
1079
123193
N486
G
V
S
Y
H
K
S
N
E
G
A
L
Y
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571877
1087
124540
K503
L
E
E
S
Y
T
D
K
K
L
R
E
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.7
96.6
84.3
N.A.
83.2
82.1
N.A.
66.1
59.8
N.A.
54.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.4
97.7
91.6
N.A.
90.8
89.3
N.A.
75.9
75.4
N.A.
71.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
60
N.A.
13.3
6.6
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
73.3
N.A.
20
6.6
N.A.
20
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
12
12
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
12
12
0
0
0
12
0
0
0
% D
% Glu:
0
12
12
0
34
0
23
12
23
12
0
12
0
0
0
% E
% Phe:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
12
0
12
0
34
0
0
0
23
23
0
0
23
12
% G
% His:
0
0
12
0
12
0
0
0
0
0
0
23
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
12
0
0
0
0
12
0
0
% I
% Lys:
0
34
0
0
0
12
12
12
23
0
0
0
0
12
12
% K
% Leu:
23
0
0
0
0
0
0
0
0
12
0
23
12
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
34
23
0
0
0
23
12
0
0
12
12
34
0
% N
% Pro:
0
12
0
12
0
0
0
0
0
0
12
0
0
0
56
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
12
0
0
12
0
% R
% Ser:
12
0
23
12
0
12
12
0
12
45
34
0
0
0
0
% S
% Thr:
0
0
0
0
12
23
34
0
0
0
12
12
0
0
23
% T
% Val:
0
34
12
0
23
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
23
12
0
12
34
34
0
0
12
56
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _