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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNP
All Species:
15.34
Human Site:
S289
Identified Species:
33.75
UniProt:
P00491
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00491
NP_000261.2
289
32118
S289
I
P
L
P
D
K
A
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001140576
289
32115
S289
I
P
L
P
D
K
A
S
_
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001092508
289
32094
S289
I
P
L
P
D
K
A
S
_
_
_
_
_
_
_
Dog
Lupus familis
XP_532617
289
32283
G289
I
P
P
P
S
K
A
G
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P23492
289
32259
S289
I
P
L
P
D
R
G
S
_
_
_
_
_
_
_
Rat
Rattus norvegicus
P85973
289
32283
N289
I
P
P
R
E
R
A
N
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079809
249
27367
Y247
S
L
I
T
N
K
A
Y
G
L
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_991218
286
31811
K285
I
V
S
N
V
V
R
K
M
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647727
353
38273
A351
L
I
R
E
I
H
L
A
S
A
_
_
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783655
290
32137
R285
L
I
G
Q
V
V
E
R
I
N
G
E
E
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05788
311
33736
V300
G
K
I
A
S
N
D
V
Q
N
L
I
A
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.8
84
N.A.
84
85.1
N.A.
N.A.
N.A.
58.1
64
N.A.
43.3
N.A.
N.A.
56.5
Protein Similarity:
100
99.6
97.5
91.3
N.A.
91
91.3
N.A.
N.A.
N.A.
70.2
78.1
N.A.
57.5
N.A.
N.A.
70.3
P-Site Identity:
100
100
100
62.5
N.A.
75
37.5
N.A.
N.A.
N.A.
20
11.1
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
62.5
N.A.
87.5
75
N.A.
N.A.
N.A.
50
11.1
N.A.
20
N.A.
N.A.
23
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
55
10
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
37
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
10
0
10
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
10
10
10
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
64
19
19
0
10
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
0
46
0
10
0
0
0
0
0
0
0
% K
% Leu:
19
10
37
0
0
0
10
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
10
0
10
0
19
0
0
0
0
0
% N
% Pro:
0
55
19
46
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
19
10
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
19
0
0
37
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
19
19
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
55
64
82
82
82
91
91
% _