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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNP
All Species:
9.09
Human Site:
T169
Identified Species:
20
UniProt:
P00491
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00491
NP_000261.2
289
32118
T169
M
S
D
A
Y
D
R
T
M
R
Q
R
A
L
S
Chimpanzee
Pan troglodytes
XP_001140576
289
32115
T169
M
S
D
A
Y
D
R
T
M
R
Q
R
A
L
S
Rhesus Macaque
Macaca mulatta
XP_001092508
289
32094
T169
M
S
D
A
Y
D
R
T
M
R
Q
R
A
L
S
Dog
Lupus familis
XP_532617
289
32283
D169
M
S
D
A
Y
D
R
D
M
R
Q
K
A
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P23492
289
32259
D169
M
S
D
A
Y
D
R
D
M
R
Q
K
A
F
T
Rat
Rattus norvegicus
P85973
289
32283
D169
M
S
D
A
Y
D
R
D
M
R
Q
K
A
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079809
249
27367
V141
I
K
D
H
I
N
M
V
G
F
A
G
Q
N
P
Zebra Danio
Brachydanio rerio
NP_991218
286
31811
D173
M
S
D
A
Y
D
R
D
L
A
Q
L
V
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647727
353
38273
D233
L
V
N
S
Y
N
K
D
L
I
N
K
A
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783655
290
32137
K173
M
S
D
V
Y
D
K
K
L
R
K
L
T
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05788
311
33736
E187
L
S
D
A
Y
D
L
E
L
R
K
L
L
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.8
84
N.A.
84
85.1
N.A.
N.A.
N.A.
58.1
64
N.A.
43.3
N.A.
N.A.
56.5
Protein Similarity:
100
99.6
97.5
91.3
N.A.
91
91.3
N.A.
N.A.
N.A.
70.2
78.1
N.A.
57.5
N.A.
N.A.
70.3
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
N.A.
N.A.
6.6
53.3
N.A.
13.3
N.A.
N.A.
40
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
20
60
N.A.
66.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
60.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
73
0
0
0
0
0
10
10
0
64
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
91
0
0
82
0
46
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
28
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
10
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
19
10
0
0
19
37
0
0
28
% K
% Leu:
19
0
0
0
0
0
10
0
37
0
0
28
10
28
0
% L
% Met:
73
0
0
0
0
0
10
0
55
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
19
0
0
0
0
10
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
64
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
64
0
0
73
0
28
0
10
0
% R
% Ser:
0
82
0
10
0
0
0
0
0
0
0
0
0
0
37
% S
% Thr:
0
0
0
0
0
0
0
28
0
0
0
0
10
0
10
% T
% Val:
0
10
0
10
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _