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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT2
All Species:
23.33
Human Site:
S118
Identified Species:
34.22
UniProt:
P00505
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00505
NP_002071.2
430
47476
S118
E
L
A
L
G
E
N
S
E
V
L
K
S
G
R
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
A112
Q
S
L
G
G
T
G
A
L
R
I
G
A
D
F
Rhesus Macaque
Macaca mulatta
XP_001103601
430
47421
S118
E
L
A
L
G
E
N
S
E
V
L
K
S
G
R
Dog
Lupus familis
XP_535278
570
61965
N258
E
L
A
L
G
E
N
N
E
V
L
K
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P05202
430
47393
N118
E
L
A
L
G
E
N
N
E
V
L
K
S
G
R
Rat
Rattus norvegicus
P00507
430
47296
S118
E
L
A
L
G
E
N
S
E
V
L
K
S
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507219
458
51187
N146
E
L
A
L
G
D
N
N
E
V
L
K
S
G
R
Chicken
Gallus gallus
P00508
423
47223
S111
E
L
A
L
G
E
N
S
E
A
F
K
S
G
R
Frog
Xenopus laevis
NP_001080255
427
47598
C115
Q
L
A
L
G
E
N
C
E
A
V
K
N
G
Q
Zebra Danio
Brachydanio rerio
NP_998544
428
47568
N116
Q
L
A
L
G
P
D
N
E
V
L
K
S
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722744
424
47167
S112
E
L
A
L
G
K
G
S
K
R
L
A
A
K
H
Honey Bee
Apis mellifera
XP_396131
429
48031
S117
K
L
A
L
G
D
N
S
D
V
V
K
N
G
L
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
G113
G
T
G
A
L
R
A
G
A
E
F
L
A
S
V
Sea Urchin
Strong. purpuratus
XP_001176520
423
46873
S119
K
L
A
F
G
Q
D
S
H
T
S
Q
E
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46643
430
47739
N116
L
K
L
A
Y
G
D
N
S
E
F
I
K
D
K
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
A116
T
G
A
L
H
I
S
A
K
F
F
S
K
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.9
98.8
71
N.A.
94.8
94.8
N.A.
82.9
83.7
81.8
79.5
N.A.
61.4
62.5
41.8
62.5
Protein Similarity:
100
66.2
99
73.5
N.A.
98.3
98.1
N.A.
87.7
91.8
91.6
88.5
N.A.
77.9
78.5
59.5
77.4
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
100
N.A.
86.6
86.6
60
73.3
N.A.
46.6
60
0
40
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
100
N.A.
100
86.6
86.6
93.3
N.A.
66.6
93.3
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.4
43.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.7
61.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
82
13
0
0
7
13
7
13
0
7
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
19
0
7
0
0
0
0
13
0
% D
% Glu:
50
0
0
0
0
44
0
0
57
13
0
0
7
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
7
25
0
0
7
13
% F
% Gly:
7
7
7
7
82
7
13
7
0
0
0
7
0
63
0
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
7
0
0
0
% I
% Lys:
13
7
0
0
0
7
0
0
13
0
0
63
13
7
7
% K
% Leu:
7
75
13
75
7
0
0
0
7
0
50
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
57
32
0
0
0
0
13
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
0
7
0
0
0
0
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
7
0
0
0
13
0
0
0
0
57
% R
% Ser:
0
7
0
0
0
0
7
44
7
0
7
7
50
13
0
% S
% Thr:
7
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
50
13
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _