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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOT2 All Species: 30.3
Human Site: S30 Identified Species: 44.44
UniProt: P00505 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00505 NP_002071.2 430 47476 S30 A A A S A R A S S W W T H V E
Chimpanzee Pan troglodytes A5A6K8 413 46215 F25 V F K L T A D F R E D P D P R
Rhesus Macaque Macaca mulatta XP_001103601 430 47421 S30 A A A S A R A S S W W T H V E
Dog Lupus familis XP_535278 570 61965 S170 G A A S A R A S S W W T H V E
Cat Felis silvestris
Mouse Mus musculus P05202 430 47393 S30 A A A S A R A S S W W T H V E
Rat Rattus norvegicus P00507 430 47296 S30 A A A S A R A S S W W T H V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507219 458 51187 N58 W V L L K I L N S W W T H V E
Chicken Gallus gallus P00508 423 47223 W25 A T A R A S S W W S H V E M G
Frog Xenopus laevis NP_001080255 427 47598 S27 A V V Q G R A S S W W S H V E
Zebra Danio Brachydanio rerio NP_998544 428 47568 S28 A V L Q L R A S S W W T E V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722744 424 47167 T25 A A L R C K S T W F S E V Q M
Honey Bee Apis mellifera XP_396131 429 48031 G29 L Y G I R S M G T W W P H V K
Nematode Worm Caenorhab. elegans Q22067 408 45475 A27 K M Y L D E T A P V K V N L T
Sea Urchin Strong. purpuratus XP_001176520 423 46873 S31 G S T A S A K S S L W D G V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46643 430 47739 S30 F G G L R S M S S W W K S V E
Baker's Yeast Sacchar. cerevisiae P23542 418 46039 R29 Q R Y G Q D Q R A T K V D L G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.9 98.8 71 N.A. 94.8 94.8 N.A. 82.9 83.7 81.8 79.5 N.A. 61.4 62.5 41.8 62.5
Protein Similarity: 100 66.2 99 73.5 N.A. 98.3 98.1 N.A. 87.7 91.8 91.6 88.5 N.A. 77.9 78.5 59.5 77.4
P-Site Identity: 100 0 100 93.3 N.A. 100 100 N.A. 46.6 20 66.6 60 N.A. 13.3 26.6 0 33.3
P-Site Similarity: 100 0 100 93.3 N.A. 100 100 N.A. 53.3 33.3 73.3 66.6 N.A. 40 40 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. 54.4 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. 70.7 61.1 N.A.
P-Site Identity: N.A. N.A. N.A. 40 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 38 38 7 38 13 44 7 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 7 7 0 0 0 7 7 13 0 0 % D
% Glu: 0 0 0 0 0 7 0 0 0 7 0 7 13 0 57 % E
% Phe: 7 7 0 0 0 0 0 7 0 7 0 0 0 0 0 % F
% Gly: 13 7 13 7 7 0 0 7 0 0 0 0 7 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 50 0 0 % H
% Ile: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 7 0 7 7 7 0 0 0 13 7 0 0 7 % K
% Leu: 7 0 19 25 7 0 7 0 0 7 0 0 0 13 0 % L
% Met: 0 7 0 0 0 0 13 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 13 0 7 0 % P
% Gln: 7 0 0 13 7 0 7 0 0 0 0 0 0 7 7 % Q
% Arg: 0 7 0 13 13 44 0 7 7 0 0 0 0 0 7 % R
% Ser: 0 7 0 32 7 19 13 57 63 7 7 7 7 0 0 % S
% Thr: 0 7 7 0 7 0 7 7 7 7 0 44 0 0 7 % T
% Val: 7 19 7 0 0 0 0 0 0 7 0 19 7 69 0 % V
% Trp: 7 0 0 0 0 0 0 7 13 63 69 0 0 0 0 % W
% Tyr: 0 7 13 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _