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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT2
All Species:
34.24
Human Site:
S360
Identified Species:
50.22
UniProt:
P00505
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00505
NP_002071.2
430
47476
S360
G
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
A340
S
M
R
S
E
L
R
A
R
L
E
A
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001103601
430
47421
S360
G
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Dog
Lupus familis
XP_535278
570
61965
S500
S
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P05202
430
47393
S360
S
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Rat
Rattus norvegicus
P00507
430
47296
S360
S
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507219
458
51187
S388
S
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Chicken
Gallus gallus
P00508
423
47223
S353
S
M
R
T
Q
L
V
S
N
L
K
K
E
G
S
Frog
Xenopus laevis
NP_001080255
427
47598
S357
S
M
R
E
Q
L
V
S
N
L
K
K
E
G
S
Zebra Danio
Brachydanio rerio
NP_998544
428
47568
S358
R
M
R
E
M
L
V
S
N
L
K
K
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722744
424
47167
D354
D
V
R
T
K
L
K
D
N
L
I
K
L
G
S
Honey Bee
Apis mellifera
XP_396131
429
48031
D359
S
M
R
Q
T
L
T
D
N
L
R
K
C
G
S
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
T339
R
H
L
M
D
L
G
T
P
G
T
W
D
H
I
Sea Urchin
Strong. purpuratus
XP_001176520
423
46873
I353
R
Q
M
S
G
R
I
I
S
M
R
E
Q
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46643
430
47739
E358
G
M
R
T
T
L
R
E
S
L
E
K
L
G
S
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
D340
K
M
R
H
A
L
R
D
H
L
V
K
L
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.9
98.8
71
N.A.
94.8
94.8
N.A.
82.9
83.7
81.8
79.5
N.A.
61.4
62.5
41.8
62.5
Protein Similarity:
100
66.2
99
73.5
N.A.
98.3
98.1
N.A.
87.7
91.8
91.6
88.5
N.A.
77.9
78.5
59.5
77.4
P-Site Identity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
80
N.A.
53.3
53.3
6.6
0
P-Site Similarity:
100
60
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
80
N.A.
66.6
60
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.4
43.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.7
61.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
7
0
0
19
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
13
7
0
0
7
0
0
13
7
57
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
7
0
7
0
0
7
0
0
0
82
0
% G
% His:
0
7
0
7
0
0
0
0
7
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
7
% I
% Lys:
7
0
0
0
7
0
7
0
0
0
57
82
0
7
0
% K
% Leu:
0
0
7
0
0
94
0
0
0
88
0
0
25
7
0
% L
% Met:
0
82
7
7
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
69
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
7
0
7
50
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
19
0
88
0
0
7
19
0
7
0
13
0
0
0
0
% R
% Ser:
50
0
0
13
0
0
0
57
13
0
0
0
0
0
75
% S
% Thr:
0
0
0
57
13
0
7
7
0
0
7
0
0
0
13
% T
% Val:
0
7
0
0
0
0
57
0
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _