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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT2
All Species:
46.97
Human Site:
S399
Identified Species:
68.89
UniProt:
P00505
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00505
NP_002071.2
430
47476
S399
E
R
L
I
K
E
F
S
I
Y
M
T
K
D
G
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
H379
E
Y
L
V
N
E
K
H
I
Y
L
L
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001103601
430
47421
S399
E
R
L
T
K
E
F
S
I
Y
M
T
K
D
G
Dog
Lupus familis
XP_535278
570
61965
S539
E
R
L
T
K
E
F
S
I
Y
M
T
K
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P05202
430
47393
S399
E
R
L
T
K
E
F
S
V
Y
M
T
K
D
G
Rat
Rattus norvegicus
P00507
430
47296
S399
E
R
L
T
K
E
F
S
V
Y
M
T
K
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507219
458
51187
S427
E
R
L
S
K
E
F
S
I
Y
M
T
K
D
G
Chicken
Gallus gallus
P00508
423
47223
S392
E
R
L
T
K
E
F
S
I
Y
M
T
K
D
G
Frog
Xenopus laevis
NP_001080255
427
47598
S396
E
R
L
I
K
E
F
S
I
Y
M
T
K
D
G
Zebra Danio
Brachydanio rerio
NP_998544
428
47568
S397
E
R
L
I
N
E
F
S
I
Y
M
T
K
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722744
424
47167
S393
Q
K
L
I
K
D
H
S
V
Y
L
T
N
D
G
Honey Bee
Apis mellifera
XP_396131
429
48031
S398
E
K
L
I
R
D
Y
S
I
Y
L
T
K
D
G
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
G378
K
V
F
L
L
R
D
G
R
I
N
I
C
G
L
Sea Urchin
Strong. purpuratus
XP_001176520
423
46873
S392
E
R
L
T
K
D
F
S
I
Y
L
T
K
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46643
430
47739
H397
D
R
L
T
S
E
Y
H
I
Y
M
T
R
N
G
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
A379
K
R
L
E
E
T
H
A
V
Y
L
V
A
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.9
98.8
71
N.A.
94.8
94.8
N.A.
82.9
83.7
81.8
79.5
N.A.
61.4
62.5
41.8
62.5
Protein Similarity:
100
66.2
99
73.5
N.A.
98.3
98.1
N.A.
87.7
91.8
91.6
88.5
N.A.
77.9
78.5
59.5
77.4
P-Site Identity:
100
40
93.3
93.3
N.A.
86.6
86.6
N.A.
93.3
93.3
100
93.3
N.A.
53.3
66.6
0
80
P-Site Similarity:
100
53.3
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
100
93.3
N.A.
86.6
100
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.4
43.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.7
61.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
0
19
7
0
0
0
0
0
0
75
0
% D
% Glu:
75
0
0
7
7
69
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
63
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
94
% G
% His:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
32
0
0
0
0
69
7
0
7
0
0
0
% I
% Lys:
13
13
0
0
63
0
7
0
0
0
0
0
69
0
0
% K
% Leu:
0
0
94
7
7
0
0
0
0
0
32
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
7
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
75
0
0
7
7
0
0
7
0
0
0
7
0
0
% R
% Ser:
0
0
0
7
7
0
0
75
0
0
0
0
0
13
0
% S
% Thr:
0
0
0
44
0
7
0
0
0
0
0
82
0
0
0
% T
% Val:
0
7
0
7
0
0
0
0
25
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
13
0
0
94
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _