Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOT2 All Species: 53.94
Human Site: S415 Identified Species: 79.11
UniProt: P00505 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00505 NP_002071.2 430 47476 S415 I S V A G V T S S N V G Y L A
Chimpanzee Pan troglodytes A5A6K8 413 46215 T395 I N V S G L T T K N L D Y V A
Rhesus Macaque Macaca mulatta XP_001103601 430 47421 S415 I S V A G V T S G N V G Y L A
Dog Lupus familis XP_535278 570 61965 S555 I S V A G V T S G N V G Y L A
Cat Felis silvestris
Mouse Mus musculus P05202 430 47393 S415 I S V A G V T S G N V G Y L A
Rat Rattus norvegicus P00507 430 47296 S415 I S V A G V T S G N V G Y L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507219 458 51187 S443 I S V A G V T S G N V G Y L A
Chicken Gallus gallus P00508 423 47223 S408 I S V A G V A S S N V G Y L A
Frog Xenopus laevis NP_001080255 427 47598 S412 I S V A G V T S A N N G Y L A
Zebra Danio Brachydanio rerio NP_998544 428 47568 S413 I S V A G V T S A N V E Y L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722744 424 47167 S409 V S M A G V T S K N V E Y L A
Honey Bee Apis mellifera XP_396131 429 48031 T414 I S V A G V T T K N V E Y V A
Nematode Worm Caenorhab. elegans Q22067 408 45475 A394 T K N V E Y V A K A I D E T V
Sea Urchin Strong. purpuratus XP_001176520 423 46873 S408 I S V A G I S S N N N A Y L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46643 430 47739 T413 I S M A G V T T G N V G Y L A
Baker's Yeast Sacchar. cerevisiae P23542 418 46039 Q395 A S I A G L N Q G N V E Y V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.9 98.8 71 N.A. 94.8 94.8 N.A. 82.9 83.7 81.8 79.5 N.A. 61.4 62.5 41.8 62.5
Protein Similarity: 100 66.2 99 73.5 N.A. 98.3 98.1 N.A. 87.7 91.8 91.6 88.5 N.A. 77.9 78.5 59.5 77.4
P-Site Identity: 100 46.6 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 93.3 86.6 86.6 N.A. 73.3 73.3 0 66.6
P-Site Similarity: 100 86.6 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 93.3 N.A. 86.6 86.6 13.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 54.4 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. 70.7 61.1 N.A.
P-Site Identity: N.A. N.A. N.A. 80 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 88 0 0 7 7 13 7 0 7 0 0 94 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % D
% Glu: 0 0 0 0 7 0 0 0 0 0 0 25 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 94 0 0 0 44 0 0 57 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 82 0 7 0 0 7 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 7 0 0 0 0 0 0 25 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 13 0 0 0 0 7 0 0 75 0 % L
% Met: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 7 0 7 94 13 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 88 0 7 0 0 7 69 13 0 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 75 19 0 0 0 0 0 7 0 % T
% Val: 7 0 75 7 0 75 7 0 0 0 75 0 0 19 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 94 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _