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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOT2 All Species: 30
Human Site: T34 Identified Species: 44
UniProt: P00505 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00505 NP_002071.2 430 47476 T34 A R A S S W W T H V E M G P P
Chimpanzee Pan troglodytes A5A6K8 413 46215 P29 T A D F R E D P D P R K V N L
Rhesus Macaque Macaca mulatta XP_001103601 430 47421 T34 A R A S S W W T H V E M G P P
Dog Lupus familis XP_535278 570 61965 T174 A R A S S W W T H V E M G P P
Cat Felis silvestris
Mouse Mus musculus P05202 430 47393 T34 A R A S S W W T H V E M G P P
Rat Rattus norvegicus P00507 430 47296 T34 A R A S S W W T H V E M G P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507219 458 51187 T62 K I L N S W W T H V E M G P P
Chicken Gallus gallus P00508 423 47223 V29 A S S W W S H V E M G P P D P
Frog Xenopus laevis NP_001080255 427 47598 S31 G R A S S W W S H V E M G P P
Zebra Danio Brachydanio rerio NP_998544 428 47568 T32 L R A S S W W T E V Q M G P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722744 424 47167 E29 C K S T W F S E V Q M G P P D
Honey Bee Apis mellifera XP_396131 429 48031 P33 R S M G T W W P H V K M G P P
Nematode Worm Caenorhab. elegans Q22067 408 45475 V31 D E T A P V K V N L T I G A Y
Sea Urchin Strong. purpuratus XP_001176520 423 46873 D35 S A K S S L W D G V E M G P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46643 430 47739 K34 R S M S S W W K S V E P A P K
Baker's Yeast Sacchar. cerevisiae P23542 418 46039 V33 Q D Q R A T K V D L G I G A Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.9 98.8 71 N.A. 94.8 94.8 N.A. 82.9 83.7 81.8 79.5 N.A. 61.4 62.5 41.8 62.5
Protein Similarity: 100 66.2 99 73.5 N.A. 98.3 98.1 N.A. 87.7 91.8 91.6 88.5 N.A. 77.9 78.5 59.5 77.4
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 73.3 13.3 86.6 80 N.A. 6.6 53.3 6.6 60
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 80 26.6 93.3 86.6 N.A. 33.3 66.6 33.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 54.4 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. 70.7 61.1 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 13 44 7 7 0 0 0 0 0 0 0 7 13 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 0 0 0 7 7 13 0 0 0 0 7 7 % D
% Glu: 0 7 0 0 0 7 0 7 13 0 57 0 0 0 0 % E
% Phe: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 0 0 0 0 7 0 13 7 75 0 0 % G
% His: 0 0 0 0 0 0 7 0 50 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 13 0 0 0 % I
% Lys: 7 7 7 0 0 0 13 7 0 0 7 7 0 0 7 % K
% Leu: 7 0 7 0 0 7 0 0 0 13 0 0 0 0 7 % L
% Met: 0 0 13 0 0 0 0 0 0 7 7 63 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 7 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 7 0 0 13 0 7 0 13 13 75 69 % P
% Gln: 7 0 7 0 0 0 0 0 0 7 7 0 0 0 0 % Q
% Arg: 13 44 0 7 7 0 0 0 0 0 7 0 0 0 0 % R
% Ser: 7 19 13 57 63 7 7 7 7 0 0 0 0 0 0 % S
% Thr: 7 0 7 7 7 7 0 44 0 0 7 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 19 7 69 0 0 7 0 0 % V
% Trp: 0 0 0 7 13 63 69 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _